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Rabbit Polyclonal Anti-ST2 antibody (STJ98813)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IHC-P, ELISA
Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-ST2 antibody.
Check alternative names for the antibodyExpand
SCBT cat No:
|Catalogue No.|| |
Anti-ST2 antibody detects endogenous ST2.
Synthetic peptide from human protein at AA range: 251-300.
|Recommended dilution|| |
IHC-P 1:50-300; ELISA 1:5000-20000
Anti-ST2 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-ST2 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Database links|| |
|Protein function|| |
Receptor for interleukin-33 (IL-33); signaling requires association of the coreceptor IL1RAP. Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function. .; Isoform B: Inhibits IL-33 signaling. .
|Protein tissue specificity|| |
Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle. Expressed on T-cells in fibrotic liver; at protein level. Overexpressed in fibrotic and cirrhotic liver. .
|Protein sequence and domain|| |
Belongs to the interleukin-1 receptor family. ; Contains 3 Ig-like C2-type (immunoglobulin-like) domains. ; Contains 1 TIR domain.
|Protein cellular localization|| |
Isoform C: Cell membrane.; Isoform B: Secreted.; Cell membrane ; Single-pass type I membrane protein .
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St John’s Laboratory Ltd.
|Product type|| |
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