Rabbit Polyclonal Anti-TGFbeta2 antibody (STJ98769)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-TGFbeta2 antibody (STJ98769)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC-P, ELISA

Recommended dilution: WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000

Recommended protocols: check protocols

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SCBT cat No:

Name

Anti-TGFbeta2 antibody

Catalogue No.

STJ98769

Reactivity

Human, Mouse, Rat

Specificity

Anti-TGFbeta2 antibody detects endogenous TGFbeta2.

Immunogen

Synthetic peptide from human protein at AA range: 61-110.

Host

Rabbit

Applications

WB, IHC-P, ELISA

Recommended dilution

WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

47+12kDa

Formulation

Anti-TGFbeta2 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-TGFbeta2 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Database links

UniProt/Swiss-Prot:P61812

Protein function

TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.

Involvement in disease

Note=A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly. Translocation t(1;7)(q41;p21) with HDAC9. .; Loeys-Dietz syndrome 4 (LDS4) [MIM:614816]: An aortic aneurysm syndrome with widespread systemic involvement. LDS4 is characterized by arterial tortuosity, aortic dissection, intracranial aneurysm and subarachnoid hemorrhage, hypertelorism, bifid uvula, pectus deformity, bicuspid aortic valve, arachnodactyly, scoliosis, foot deformities, dural ectasia, joint hyperflexibility, and thin skin with easy bruising and striae. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Note=Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD). NSAD is a frequently asymptomatic but potentially lethal disease characterized by thoracic aortic aneurysms and dissections without additional syndromic features. .

Protein sequence and domain

Belongs to the TGF-beta family.

Protein post-translational modifications

The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. .

Protein cellular localization

Secreted.

Note

AntibodyPlus can customize Anti-TGFbeta2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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