Rabbit Polyclonal Anti-WIPI2 antibody (STJ98939)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-WIPI2 antibody (STJ98939)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|ATG18B antibody|Atg21 antibody|CGI 50 antibody|DKFZp434J154 antibody|DKFZp686P02188 antibody|FLJ12979 antibody|FLJ14217 antibody|FLJ42984 antibody|WD repeat domain phosphoinositide-interacting protein 2 antibody|WD repeat domain, phosphoinositide interacting 2 antibody|WD40 repeat protein interacting with phosphoinositides 2 antibody|WIPI 2 antibody|WIPI-2 antibody|WIPI2 antibody|WIPI2_HUMAN antibody|WIPI49 like protein 2 antibody|WIPI49-like protein 2 antibody|Anti-WIPI2 antibody [2A2] (ab105459)
SCBT cat No:

Name

Anti-WIPI2 antibody

Catalogue No.

STJ98939

Reactivity

Human, Mouse, Rat

Specificity

Anti-WIPI2 antibody detects endogenous WIPI2 protein.

Immunogen

Recombinant Protein of WIPI2.

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

49kDa

Formulation

Anti-WIPI2 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-WIPI2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

ATG18B antibody, Atg21 antibody, CGI 50 antibody, DKFZp434J154 antibody, DKFZp686P02188 antibody, FLJ12979 antibody, FLJ14217 antibody, FLJ42984 antibody, WD repeat domain phosphoinositide-interacting protein 2 antibody, WD repeat domain, phosphoinositide interacting 2 antibody, WD40 repeat protein interacting with phosphoinositides 2 antibody, WIPI 2 antibody, WIPI-2 antibody, WIPI2 antibody, WIPI2_HUMAN antibody, WIPI49 like protein 2 antibody, WIPI49-like protein 2 antibody

Database links

UniProt/Swiss-Prot:Q9Y4P8

Protein function

Early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to phosphatidylinositol 3-phosphate (PtdIns3P). May bind PtdIns3P. .; Isoform 4: Recruits the ATG12-ATG5-ATG16L1 complex to omegasomes and preautophagosomal structures, resulting in ATG8 family proteins lipidation and starvation-induced autophagy. Isoform 4 is also required for autophagic clearance of pathogenic bacteria. Isoform 4 binds the membrane surrounding Salmonella and recruits the ATG12-5-16L1 complex, initiating LC3 conjugation, autophagosomal membrane formation, and engulfment of Salmonella. .

Protein tissue specificity

Ubiquitously expressed (at protein level). Highly expressed in heart, skeletal muscle and pancreas. Expression is down-regulated in pancreatic and in kidney tumors. .

Protein sequence and domain

Belongs to the WD repeat SVP1 family. ; Contains 7 WD repeats. The FRRG motif is required for recruitment to PtdIns3P.

Protein cellular localization

Preautophagosomal structure membrane ; Peripheral membrane protein ; Cytoplasmic side . Note=Localizes to omegasomes membranes which are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Enriched at preautophagosomal structure membranes in response to PtdIns3P. .

Research area

All research areas>Signaling Intermediates>WIPI
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize Anti-WIPI2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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