Rabbit polyclonal AP3B1 antibody (A7019)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal AP3B1 antibody (A7019)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal AP3B1 antibody.

Alternative names:

Check alternative names for the antibody

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PE antibody, HPS antibody, HPS2 antibody, ADTB3 antibody, ADTB3A antibody
Adaptor protein complex AP-3 subunit beta-1 antibody|Adaptor protein complex AP3 beta1 subunit antibody|ADTB3 antibody|ADTB3A antibody|AP-3 complex subunit beta-1 antibody|AP3 complex beta1 subunit antibody|AP3B1 antibody|AP3B1_HUMAN antibody|Beta-3A-adaptin antibody|Beta3A adaptin antibody|Clathrin assembly protein complex 3 beta 1 large chain antibody|Clathrin assembly protein complex 3 beta-1 large chain antibody|HPS antibody|PE antibody|Anti-HPS2 antibody – C-terminal (ab197155)

SCBT cat No: sc-517083|sc-69447|sc-13384|

Name

Rabbit polyclonal AP3B1 antibody

Catalogue No.

A7019

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human AP3B1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 121kDa/Observed: Refer to figures

Formulation

AP3B1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

AP3B1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PE antibody, HPS antibody, HPS2 antibody, ADTB3 antibody, ADTB3A antibody

Database links

Human UniProt/Swiss-Prot:O00203

Protein names

PE, HPS, HPS2, ADTB3, ADTB3A

Protein function

Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Protein tissue specificity

Ubiquitously expressed.

Protein sequence and domain

Belongs to the adaptor complexes large subunit family.

Protein post-translational modifications

Phosphorylated on serine residues.

Protein cellular localization

Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Golgi apparatus . Note: Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.

Background

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene.

Research area

All research areas>Transport and Trafficking>Adaptin Related Adapter Protein
(View all antibody categories related to Transport and Trafficking)

Note

AntibodyPlus can customize AP3B1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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