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Rabbit Polyclonal ARAP1 antibody (A10466)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit Polyclonal ARAP1 antibody.
Check alternative names for the antibodyExpand
2410002L19Rik antibody|ANK repeat and PH domain-containing protein 1 antibody|ARAP 1 antibody|Arap1 antibody|ARAP1_HUMAN antibody|Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domains containing protein 1 antibody|Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domain containing protein 1 antibody|Arf-GAP with Rho-GAP domain antibody|CENT D2 antibody|Centaurin delta 2 antibody|Centaurin delta2 antibody|Centaurin-delta-2 antibody|CENTD 2 antibody|CENTD2 antibody|Cnt d2 antibody|Cnt-d2 antibody|Cntd2 antibody|KIAA0782 antibody|MGC176140 antibody|mKIAA0782 antibody|Anti-ARAP1 antibody (ab5912)
SCBT cat No: sc-393138|
Rabbit Polyclonal ARAP1 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human ARAP1
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
ARAP1 antibody was tube-contained.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
Human UniProt/Swiss-Prot:<a href="http://www.uniprot.org/uniprot/Q96P48">Q96P48</a>
|Protein names|| |
|Protein function|| |
Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5 (By similarity).
|Protein tissue specificity|| |
Detected in heart, skeletal muscle, spleen, kidney, liver, placenta, lung, peripheral blood leukocytes, adrenal gland, bone marrow, brain, lymph node, mammary gland, prostate, spinal cord, stomach, thyroid and trachea.
|Protein sequence and domain|| |
Contains 1 Arf-GAP domain.; Contains 4 PH domains.; Contains 1 Ras-associating domain.; Contains 1 Rho-GAP domain.; Contains 1 SAM (sterile alpha motif) domain.
|Protein cellular localization|| |
Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell membrane. Note=Associated with Golgi stacks in resting cells. Throughout the cytoplasm and in surface protrusion in cells that are in the process of attaching to a surface and spreading.
The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
AntibodyPlus can customize ARAP1 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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