Rabbit polyclonal AREG antibody (A1860)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal AREG antibody (A1860)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

AR antibody, CRDGF antibody, MGC13647 antibody, SDGF antibody
A REG antibody|Amphiregulin antibody|Amphiregulin B antibody|AR antibody|AREG antibody|AREG_HUMAN antibody|AREGB antibody|Colorectum cell derived growth factor antibody|Colorectum cell-derived growth factor antibody|CRDGF antibody|MGC13647 antibody|Schwannoma derived growth factor antibody|SDGF antibody|Anti-Amphiregulin antibody (ab33558)

SCBT cat No: sc-5797|

Name

Rabbit polyclonal AREG antibody

Catalogue No.

A1860

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human AREG

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 28kDa/Observed: Refer to Figures

Formulation

AREG antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

AREG antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

AR antibody, CRDGF antibody, MGC13647 antibody, SDGF antibody

Database links

Human UniProt/Swiss-Prot:P15514

Protein names

AR, CRDGF, MGC13647, SDGF

Protein function

Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.

Protein sequence and domain

Belongs to the amphiregulin family.; Contains 1 EGF-like domain.

Protein cellular localization

Membrane; Single-pass membrane protein.

Background

Amphiregulin (AREG) is one of the ligands of the epidermal growth factor receptor (EGFR). AREG plays a central role in mammary gland development and branching morphogenesis in organs and is expressed both in physiological and in cancerous tissues. The AREG protein is synthesized as a 252-amino acid transmembrane precursor, pro-AREG. At the plasma membrane, pro-AREG is subjected to sequential proteolytic cleavages within its ectodomain and is then released as the soluble AREG protein. Depending on the cell type and microenvironment, AREG can be produced in multiple cellular and mature forms using alternative pro-AREG cleavage sites and glycosylation motifs.

Research area

All research areas>Growth Factors and Hormones>Amphiregulin
(View all antibody categories related to Growth Factors and Hormones)

Note

AntibodyPlus can customize AREG antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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