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Rabbit polyclonal ARF6 antibody (A3162)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:100 IF 1:50 – 1:100
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
antibody|BING 2 antibody|BING2 antibody|CENP-C binding protein antibody|DAP 6 antibody|DAP6 antibody|DAXX antibody|DAXX_HUMAN antibody|Death associated protein 6 antibody|Death domain associated protein 6 antibody|Death domain associated protein antibody|Death domain-associated protein 6 antibody|EAP 1 antibody|EAP1 antibody|ETS1 associated protein 1 antibody|ETS1-associated protein 1 antibody|Fas binding protein antibody|Fas death domain associated protein antibody|Fas death domain-associated protein antibody|hDaxx antibody|MGC126245 antibody|MGC126246 antibody|Anti-ARF6 antibody (ab77581)
SCBT cat No: sc-7971|
Rabbit polyclonal ARF6 antibody
|Catalogue No.|| |
Human, Mouse, Rat
A synthetic peptide of human ARF6
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 20kDa/Observed: Refer to Figures
ARF6 antibody was tube-contained.
ARF6 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. May also modulate vesicle budding and uncoating within the Golgi apparatus. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase.
|Protein tissue specificity|| |
Ubiquitous, with higher levels in heart, substantia nigra, and kidney.
|Protein sequence and domain|| |
Belongs to the small GTPase superfamily. Arf family.
|Protein cellular localization|| |
Golgi apparatus. Cell membrane; Lipid-anchor. Endosome membrane; Lipid-anchor. Recycling endosome membrane ; Lipid-anchor . Cell projection, filopodium membrane; Lipid-anchor. Midbody . Cytoplasm . Cleavage furrow . Note: Distributed throughout the cytoplasm during metaphase. Transiently detected at the ingressing cleavage furrow during mitotic cytokinesis. Recruited to the midbody at later stages of cytokinesis; this requires interaction with KIF23 (By similarity). Recruited to the cell membrane in association with CYTH2 and ARL4C. Colocalizes with DAB2IP at the plasma membrane and endocytic vesicles.
This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7.
AntibodyPlus can customize ARF6 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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