Rabbit polyclonal ARFGAP1 antibody (A7118)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal ARFGAP1 antibody (A7118)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ARFGAP1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

ARF1GAP antibody, HRIHFB2281 antibody
ADP ribosylation factor 1 GTPase activating protein antibody|ADP ribosylation factor GTPase activating protein 1 antibody|ADP-ribosylation factor 1 GTPase-activating protein antibody|ADP-ribosylation factor GTPase-activating protein 1 antibody|ARF GAP 1 antibody|ARF1 directed GTPase activating protein antibody|ARF1 GAP antibody|ARF1-directed GTPase-activating protein antibody|ARF1GAP antibody|ARFG1_HUMAN antibody|Arfgap1 antibody|GAP protein antibody|HRIHFB2281 antibody|Anti-ARFGAP1 antibody [EPR13650] (ab183746)

SCBT cat No: sc-271303|sc-98714|

Name

Rabbit polyclonal ARFGAP1 antibody

Catalogue No.

A7118

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ARFGAP1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 45kDa/Observed: Refer to figures

Formulation

ARFGAP1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ARFGAP1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ARF1GAP antibody, HRIHFB2281 antibody

Database links

Human UniProt/Swiss-Prot:Q8N6T3

Protein names

ARF1GAP, HRIHFB2281

Protein function

GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle’s fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine (By similarity).

Protein sequence and domain

The region downstream of Arf-GAP domain is essential to GAP activity in vivo. This region may be required for its targeting to Golgi membranes (By similarity).Contains 1 Arf-GAP domain.

Protein cellular localization

Cytoplasm . Golgi apparatus . Note: Associates with the Golgi complex.

Background

The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.

Note

AntibodyPlus can customize ARFGAP1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!