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Rabbit polyclonal ARG2 antibody (A6355)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal ARG2 antibody.
Check alternative names for the antibodyExpand
ARG2 antibody|ARGI2_HUMAN antibody|Arginase II mitochondrial antibody|Arginase type II antibody|Arginase-2 antibody|arginase-2, mitochondrial antibody|Kidney arginase antibody|Kidney type arginase antibody|Kidney-type arginase antibody|L arginine amidinohydrolase antibody|L arginine ureahydrolase antibody|mitochondrial antibody|Non hepatic arginase antibody|Non-hepatic arginase antibody|Nonhepatic arginase antibody|Type II arginase antibody|Anti-Arg2 antibody [EPR9473] (ab137069)
SCBT cat No: sc-393496|sc-374420|sc-271443|sc-20151|sc-18357|sc-18360|
Rabbit polyclonal ARG2 antibody
|Catalogue No.|| |
Recombinant protein of human ARG2
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 38kDa/Observed: Refer to Figures
ARG2 antibody was tube-contained.
ARG2 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
|Protein tissue specificity|| |
Expressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas.
|Protein sequence and domain|| |
Belongs to the arginase family.
|Protein cellular localization|| |
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.
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|Product type|| |
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