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Rabbit polyclonal ATAD3A antibody (A8230)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:100 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal ATAD3A antibody.
Check alternative names for the antibodyExpand
AAA-ATPase TOB3 antibody|Atad3a antibody|ATPase family AAA domain containing protein 3A antibody|ATPase family AAA domain-containing protein 3 antibody|ATPase family, AAA domain containing 3A antibody|FLJ10709 antibody|FLJ35514 antibody|Tob3 antibody|Anti-ATAD3A antibody (ab112572)
SCBT cat No: sc-376185|sc-292156|
Rabbit polyclonal ATAD3A antibody
|Catalogue No.|| |
Recombinant protein of human ATAD3A
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 71kDa/Observed: Refer to figures
ATAD3A antibody was tube-contained.
ATAD3A antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis.
|Protein tissue specificity|| |
Overexpressed in lung adenocarcinomas (at protein level).
|Protein sequence and domain|| |
The transmembrane domain and a C-terminal adjacent region contain all information necessary for mitochondrial targeting.Belongs to the AAA ATPase family.
|Protein cellular localization|| |
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion matrix, mitochondrion nucleoid. Note: In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane. The N-terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids.
ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007
AntibodyPlus can customize ATAD3A antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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