Rabbit polyclonal ATAD3B antibody (A8268)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ATAD3B antibody (A8268)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ATAD3B antibody.

Alternative names:

Check alternative names for the antibody

Expand

TOB3 antibody, AAA-TOB3 antibody
AAA ATPase TOB3 antibody|AAA-TOB3 antibody|ATPase family AAA domain containing protein 3B antibody|ATPase family, AAA domain containing 3A antibody|ATPase family, AAA domain containing 3B antibody|ATPase family, AAA domain containing, member 3B antibody|TOB3 antibody|Anti-ATAD3B antibody (ab112563)

SCBT cat No: sc-514615|

Name

Rabbit polyclonal ATAD3B antibody

Catalogue No.

A8268

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ATAD3B

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 73kDa/Observed: Refer to figures

Formulation

ATAD3B antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ATAD3B antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

TOB3 antibody, AAA-TOB3 antibody

Database links

Human UniProt/Swiss-Prot:Q5T9A4

Protein names

TOB3, AAA-TOB3

Protein function

May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes.

Protein tissue specificity

Tends to be down-regulated in differentiated cells and re-expressed in pluripotent stem cells or cancer cells (at protein level).

Protein sequence and domain

Belongs to the AAA ATPase family.

Protein cellular localization

Mitochondrion inner membrane ; Peripheral membrane protein . Note: Has been found to co-purify with nucleoids . Since it does not face the mitochondrial matrix, the association with nucleoids could be mediated by ATAD3A.

Background

ATAD3A (MIM 612316) and ATAD3B are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007

Note

AntibodyPlus can customize ATAD3B antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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