Rabbit polyclonal ATF1 antibody (A5791)


Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal ATF1 antibody (A5791)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ATF1 antibody.

Alternative names:

Check alternative names for the antibody


TREB36 antibody, EWS-ATF1 antibody, FUS/ATF-1 antibody
Activating transcription factor 1 antibody|ATF 1 antibody|atf1 antibody|ATF1 EWS fusion gene antibody|ATF1 FUS fusion gene antibody|ATF1_HUMAN antibody|cAMP dependent transcription factor 1 antibody|cAMP-dependent transcription factor ATF-1 antibody|Cyclic AMP dependent transcription factor ATF 1 antibody|Cyclic AMP dependent transcription factor ATF1 antibody|Cyclic AMP-dependent transcription factor ATF-1 antibody|EWS AFT1 antibody|FUS ATF 1 antibody|FUS/ATF 1 antibody|Protein TREB36 antibody|RNA binding protein activating transcription factor 1 fusion protein antibody|TREB 36 antibody|TREB36 antibody|TREB36 protein antibody|Phospho anti-ATF1 (S63) antibody [EP1591(2)Y] (ab76085)

SCBT cat No: sc-270|sc-53172|sc-243|sc-241|sc-365525|sc-187|sc-242|


Rabbit polyclonal ATF1 antibody

Catalogue No.



Human, Mouse, Rat


Recombinant protein of human ATF1





Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200







Molecular weight

Predicted: 29kDa/Observed: Refer to Figures


ATF1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


ATF1 antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

TREB36 antibody, EWS-ATF1 antibody, FUS/ATF-1 antibody

Database links

Human UniProt/Swiss-Prot:P18846

Protein names


Protein function

This protein binds the cAMP response element (CRE) (consensus: 5′-GTGACGT[AC][AG]-3′), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.

Protein sequence and domain

Belongs to the bZIP family. ATF subfamily.; Contains 1 bZIP (basic-leucine zipper) domain.; Contains 1 KID (kinase-inducible) domain.

Protein post-translational modifications

Phosphorylated at Ser-198 by HIPK2 in response to genotoxic stress. This phosphorylation promotes transcription repression of FTH1 and other antioxidant detoxification genes. The CDK3-mediated phosphorylation at Ser-63 promotes its transactivation and transcriptional activities. Phosphorylated at Ser-63 by RPS6KA4 and RPS6KA5 in response to mitogenic or stress stimuli.

Protein cellular localization



This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.

Research area

All research areas>Transcription Regulators>ATF
(View all antibody categories related to Transcription Regulators)


AntibodyPlus can customize ATF1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:

Welcome to AntibodyPlus!