Rabbit polyclonal ATL1 antibody (A5302)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ATL1 antibody (A5302)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ATL1 antibody.

Alternative names:

Check alternative names for the antibody

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FSP1 antibody, GBP3 antibody, SPG3 antibody, HSN1D antibody, SPG3A antibody, AD-FSP antibody, atlastin1 antibody
AD FSP antibody|atl1 antibody|ATLA1_HUMAN antibody|Atlastin GTPase 1 antibody|Atlastin-1 antibody|Atlastin1 antibody|Brain specific GTP binding protein antibody|Brain-specific GTP-binding protein antibody|FSP1 antibody|GBP-3 antibody|GBP3 antibody|GTP-binding protein 3 antibody|Guanine nucleotide-binding protein 3 antibody|Guanylate binding protein 3 antibody|hGBP3 antibody|HSN1D antibody|Spastic paraplegia 3 protein A antibody|SPG 3A antibody|SPG3 antibody|SPG3A antibody|SPG3A gene antibody|Anti-SPG3A antibody (ab58273)

SCBT cat No: sc-374175|sc-376619|sc-67232|

Name

Rabbit polyclonal ATL1 antibody

Catalogue No.

A5302

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ATL1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 63kDa/Observed: Refer to Figures

Formulation

ATL1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ATL1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

FSP1 antibody, GBP3 antibody, SPG3 antibody, HSN1D antibody, SPG3A antibody, AD-FSP antibody, atlastin1 antibody

Database links

Human UniProt/Swiss-Prot:Q8WXF7

Protein names

FSP1, GBP3, SPG3, HSN1D, SPG3A, AD-FSP, atlastin1

Protein function

GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development.

Protein tissue specificity

Expressed predominantly in the adult and fetal central nervous system. Measurable expression in all tissues examined, although expression in adult brain is at least 50-fold higher than in other tissues. Detected predominantly in pyramidal neurons in the cerebral cortex and the hippocampus of the brain. Expressed in upper and lower motor neurons (at protein level).

Protein sequence and domain

Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily.; Contains 1 GB1/RHD3-type G (guanine nucleotide-binding) domain.

Protein cellular localization

Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Cell projection, axon .

Background

The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.

Research area

All research areas>Neurobiology>Atlastin
(View all antibody categories related to Neurobiology)

Note

AntibodyPlus can customize ATL1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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