Rabbit polyclonal ATP2B2 antibody (A6875)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ATP2B2 antibody (A6875)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ATP2B2 antibody.

Alternative names:

Check alternative names for the antibody

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PMCA2 antibody, PMCA2a antibody, PMCA2i antibody
AT2B1_HUMAN antibody|ATP2B1 antibody|ATP2B2 antibody|ATP2B3 antibody|ATP2B4 antibody|ATPase Ca++ transporting plasma membrane 1 antibody|ATPase Ca++ transporting plasma membrane 2 antibody|ATPase Ca++ transporting plasma membrane 3 antibody|ATPase Ca++ transporting plasma membrane 4 antibody|Plasma membrane calcium ATPase isoform 1 antibody|Plasma membrane calcium pump isoform 1 antibody|Plasma membrane calcium transporting ATPase 1 antibody|Plasma membrane calcium transporting ATPase 2 antibody|Plasma membrane calcium transporting ATPase 3 antibody|Plasma membrane calcium transporting ATPase 4 antibody|Plasma membrane calcium-transporting ATPase 1 antibody|PMCA1 antibody|PMCA2 antibody|PMCA3 antibody|PMCA4 antibody|Anti-Calcium Pump pan PMCA ATPase antibody [5F10] (ab2825)

SCBT cat No: sc-398013|sc-367384|sc-22076|sc-390148|

Name

Rabbit polyclonal ATP2B2 antibody

Catalogue No.

A6875

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ATP2B2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 137kDa/Observed: Refer to figures

Formulation

ATP2B2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ATP2B2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PMCA2 antibody, PMCA2a antibody, PMCA2i antibody

Database links

Human UniProt/Swiss-Prot:Q01814

Protein names

PMCA2, PMCA2a, PMCA2i

Protein function

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.

Protein tissue specificity

Mainly expressed in brain cortex. Found in low levels in skeletal muscle, heart muscle, stomach, liver, kidney and lung. Isoforms containing segment B are found in brain cortex and at low levels in other tissues. Isoforms containing segments X and W are found at low levels in all tissues. Isoforms containing segment A and segment Z are found at low levels in skeletal muscle and heart muscle.

Protein sequence and domain

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.

Protein cellular localization

Cell junction, synapse . Cell membrane ; Multi-pass membrane protein .

Background

The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified.

Note

AntibodyPlus can customize ATP2B2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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