Rabbit polyclonal ATP6AP2 antibody (A6531)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ATP6AP2 antibody (A6531)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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PRR antibody, M8-9 antibody, MRXE antibody, RENR antibody, XMRE antibody, XPDS antibody, HT028 antibody, MRXSH antibody, ELDF10 antibody, ATP6IP2 antibody, MSTP009 antibody, APT6M8-9 antibody, ATP6M8-9 antibody
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SCBT cat No: sc-67390|sc-55025|

Name

Rabbit polyclonal ATP6AP2 antibody

Catalogue No.

A6531

Reactivity

Human

Immunogen

Recombinant protein of human ATP6AP2

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 39kDa/Observed: Refer to figures

Formulation

ATP6AP2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ATP6AP2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PRR antibody, M8-9 antibody, MRXE antibody, RENR antibody, XMRE antibody, XPDS antibody, HT028 antibody, MRXSH antibody, ELDF10 antibody, ATP6IP2 antibody, MSTP009 antibody, APT6M8-9 antibody, ATP6M8-9 antibody

Database links

Human UniProt/Swiss-Prot:O75787

Protein names

PRR, M8-9, MRXE, RENR, XMRE, XPDS, HT028, MRXSH, ELDF10, ATP6IP2, MSTP009, APT6M8-9, ATP6M8-9

Protein function

Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS).

Protein tissue specificity

Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncytiotrophoblast cells in the mature fetal placenta.

Protein post-translational modifications

Phosphorylated.

Protein cellular localization

Membrane ; Single-pass type I membrane protein .

Background

This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.

Research area

All research areas>Membrane Receptors>Renin Receptor
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize ATP6AP2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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