Rabbit polyclonal ATRIP antibody (A7139)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ATRIP antibody (A7139)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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AGS1 antibody|ATR interacting protein antibody|ATR-interacting protein antibody|Atrip antibody|ATRIP_HUMAN antibody|DKFZp762J2115 antibody|FLJ12343 antibody|MGC20625 antibody|MGC21482 antibody|MGC26740 antibody|Anti-ATRIP antibody [EPR8072(2)] (ab175221)

SCBT cat No: sc-365383|

Name

Rabbit polyclonal ATRIP antibody

Catalogue No.

A7139

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human ATRIP

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 86kDa/Observed: Refer to figures

Formulation

ATRIP antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ATRIP antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q8WXE1

Protein function

Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.

Protein tissue specificity

Ubiquitous.

Protein sequence and domain

The EEXXXDDL motif is required for the interaction with catalytic subunit PRKDC and its recruitment to sites of DNA damage.Belongs to the ATRIP family.

Protein post-translational modifications

Phosphorylated by ATR.

Protein cellular localization

Nucleus . Note: Redistributes to discrete nuclear foci upon DNA damage.

Background

This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

Research area

All research areas>Cell Cycle Proteins>ATRIP
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize ATRIP antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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