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Rabbit polyclonal AUH antibody (A7424)
$69.00–$259.00
Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.
Rabbit polyclonal AUH antibody (A7424)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
Recommended dilution:
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Image descriptions:
Click or hover above images to see image description for Rabbit polyclonal AUH antibody.
Alternative names:
Check alternative names for the antibody
Expand3 methylglutaconyl CoA hydratase antibody|AU binding protein/enoyl CoA hydratase antibody|AU RNA binding protein/enoyl CoA hydratase antibody|AU RNA binding protein/enoyl Coenzyme A hydratase antibody|AU specific RNA binding antibody|AU specific RNA binding enoyl CoA hydratase antibody|Methylglutaconyl CoA hydratase antibody|Methylglutaconyl CoA hydratase mitochondrial antibody|MGA Type I antibody|Anti-AUH antibody [EPR11087(B)] (ab155980)
SCBT cat No: sc-82521|
Name | Rabbit polyclonal AUH antibody |
---|---|
Catalogue No. | A7424 |
Reactivity | Human, Mouse, Rat |
Immunogen | Recombinant protein of human AUH |
Host | Rabbit |
Applications | WB, IHC |
Recommended dilution | WB 1:500 – 1:2000 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Molecular weight | Predicted: 36kDa/Observed: Refer to figures |
Formulation | AUH antibody was tube-contained. |
Purification | AUH antibody was purified using affinity purification. |
Storage | Store at -20 Celsius degree. Avoid freeze / thaw cycles. |
Database links | Human UniProt/Swiss-Prot:Q13825 |
Protein function | Catalyzes the conversion of 3-methylglutaconyl-CoA to 3-hydroxy-3-methylglutaryl-CoA. Has very low enoyl-CoA hydratase activity. Was originally identified as RNA-binding protein that binds in vitro to clustered 5′-AUUUA-3′ motifs. |
Protein sequence and domain | Belongs to the enoyl-CoA hydratase/isomerase family. |
Protein cellular localization | Mitochondrion . |
Background | The methylglutaconyl-CoA hydratase, mitochondrial protein binds to the AU-rich element (ARE), a common element found in the 3′ UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity. A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92% identity with the human protein. It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein. Human AUH is expressed as a single mRNA species of 1.8 kb, and translated as a 40-kDa precursor protein which is subsequently processed to a 32-kDa mature form. |
Note | AntibodyPlus can customize AUH antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation. |
Product type | Primary antibody |
Supplier | ABclonal Inc. |
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