No products in the cart.
Home/Products/Product type/Primary antibody
Rabbit polyclonal AUH antibody (A7424)
$69.00–$259.00
Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.
Rabbit polyclonal AUH antibody (A7424)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
Recommended dilution:
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Image descriptions:
Click or hover above images to see image description for Rabbit polyclonal AUH antibody.
Alternative names:
Check alternative names for the antibody
Expand3 methylglutaconyl CoA hydratase antibody|AU binding protein/enoyl CoA hydratase antibody|AU RNA binding protein/enoyl CoA hydratase antibody|AU RNA binding protein/enoyl Coenzyme A hydratase antibody|AU specific RNA binding antibody|AU specific RNA binding enoyl CoA hydratase antibody|Methylglutaconyl CoA hydratase antibody|Methylglutaconyl CoA hydratase mitochondrial antibody|MGA Type I antibody|Anti-AUH antibody [EPR11087(B)] (ab155980)
SCBT cat No: sc-82521|
| Name | Rabbit polyclonal AUH antibody |
|---|---|
| Catalogue No. | A7424 |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Recombinant protein of human AUH |
| Host | Rabbit |
| Applications | WB, IHC |
| Recommended dilution | WB 1:500 – 1:2000 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Molecular weight | Predicted: 36kDa/Observed: Refer to figures |
| Formulation | AUH antibody was tube-contained. |
| Purification | AUH antibody was purified using affinity purification. |
| Storage | Store at -20 Celsius degree. Avoid freeze / thaw cycles. |
| Database links | Human UniProt/Swiss-Prot:Q13825 |
| Protein function | Catalyzes the conversion of 3-methylglutaconyl-CoA to 3-hydroxy-3-methylglutaryl-CoA. Has very low enoyl-CoA hydratase activity. Was originally identified as RNA-binding protein that binds in vitro to clustered 5′-AUUUA-3′ motifs. |
| Protein sequence and domain | Belongs to the enoyl-CoA hydratase/isomerase family. |
| Protein cellular localization | Mitochondrion . |
| Background | The methylglutaconyl-CoA hydratase, mitochondrial protein binds to the AU-rich element (ARE), a common element found in the 3′ UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity. A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92% identity with the human protein. It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein. Human AUH is expressed as a single mRNA species of 1.8 kb, and translated as a 40-kDa precursor protein which is subsequently processed to a 32-kDa mature form. |
| Note | AntibodyPlus can customize AUH antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation. |
| Product type | Primary antibody |
| Supplier | ABclonal Inc. |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below:
Reviews
There are no reviews yet.