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Rabbit polyclonal BAAT antibody (A7646)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal BAAT antibody.
Check alternative names for the antibodyExpand
BAT antibody, BACAT antibody
FLJ20300 antibody|BAAT antibody|BAAT_HUMAN antibody|BACAT antibody|BAT antibody|Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) antibody|Bile acid CoA:amino acid N acyltransferase antibody|Bile acid Coenzyme A amino acid N acyltransferase glycine N choloyltransferase antibody|Bile acid Coenzyme A: amino acid N acyltransferase antibody|Bile acid-CoA:amino acid N-acyltransferase antibody|Glycine N choloyltransferase antibody|Glycine N-choloyltransferase antibody|Long chain fatty acyl CoA hydrolase antibody|Long-chain fatty-acyl-CoA hydrolase antibody|MGC104432 antibody|Anti-BAAT antibody (ab83882)
SCBT cat No: sc-100475|
Rabbit polyclonal BAAT antibody
|Catalogue No.|| |
Recombinant protein of human BAAT
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 46kDa/Observed: Refer to figures
BAAT antibody was tube-contained.
BAAT antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
BAT antibody, BACAT antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.
|Protein tissue specificity|| |
Expressed in liver, gallbladder mucosa and pancreas.
|Protein sequence and domain|| |
Belongs to the C/M/P thioester hydrolase family.
|Protein cellular localization|| |
The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
AntibodyPlus can customize BAAT antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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