Rabbit polyclonal BAAT antibody (A7646)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal BAAT antibody (A7646)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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BAT antibody, BACAT antibody
FLJ20300 antibody|BAAT antibody|BAAT_HUMAN antibody|BACAT antibody|BAT antibody|Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) antibody|Bile acid CoA:amino acid N acyltransferase antibody|Bile acid Coenzyme A amino acid N acyltransferase glycine N choloyltransferase antibody|Bile acid Coenzyme A: amino acid N acyltransferase antibody|Bile acid-CoA:amino acid N-acyltransferase antibody|Glycine N choloyltransferase antibody|Glycine N-choloyltransferase antibody|Long chain fatty acyl CoA hydrolase antibody|Long-chain fatty-acyl-CoA hydrolase antibody|MGC104432 antibody|Anti-BAAT antibody (ab83882)

SCBT cat No: sc-100475|

Name

Rabbit polyclonal BAAT antibody

Catalogue No.

A7646

Reactivity

Human

Immunogen

Recombinant protein of human BAAT

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 46kDa/Observed: Refer to figures

Formulation

BAAT antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

BAAT antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

BAT antibody, BACAT antibody

Database links

Human UniProt/Swiss-Prot:Q14032

Protein names

BAT, BACAT

Protein function

Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.

Protein tissue specificity

Expressed in liver, gallbladder mucosa and pancreas.

Protein sequence and domain

Belongs to the C/M/P thioester hydrolase family.

Protein cellular localization

Cytoplasm .

Background

The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.

Note

AntibodyPlus can customize BAAT antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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