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Rabbit polyclonal BAZ1A antibody (A9866)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal BAZ1A antibody.
Check alternative names for the antibodyExpand
Acf1 antibody||Anti-ACF1 / BAZ1A antibody [EPR15826] – C-terminal (ab187670)
SCBT cat No: sc-393164|sc-10627|
Rabbit polyclonal BAZ1A antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human BAZ1A
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 179kDa/Observed: Refer to figures
BAZ1A antibody was tube-contained.
BAZ1A antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.; Component of the histone-fold protein complex CHRAC complex which faciliates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions.
|Protein tissue specificity|| |
Highly expressed in testis and at low or undetectable levels in other tissues analyzed.
|Protein sequence and domain|| |
Belongs to the WAL family.; Contains 1 bromo domain.; Contains 1 DDT domain.; Contains 1 PHD-type zinc finger.; Contains 1 WAC domain.
|Protein cellular localization|| |
Nucleus. Note: May target the CHRAC complex to heterochromatin.
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|Product type|| |
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