Rabbit polyclonal BAZ1A antibody (A9866)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal BAZ1A antibody (A9866)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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Acf1 antibody||Anti-ACF1 / BAZ1A antibody [EPR15826] – C-terminal (ab187670)

SCBT cat No: sc-393164|sc-10627|

Name

Rabbit polyclonal BAZ1A antibody

Catalogue No.

A9866

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human BAZ1A

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 179kDa/Observed: Refer to figures

Formulation

BAZ1A antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

BAZ1A antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q9NRL2

Protein function

Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.; Component of the histone-fold protein complex CHRAC complex which faciliates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions.

Protein tissue specificity

Highly expressed in testis and at low or undetectable levels in other tissues analyzed.

Protein sequence and domain

Belongs to the WAL family.; Contains 1 bromo domain.; Contains 1 DDT domain.; Contains 1 PHD-type zinc finger.; Contains 1 WAC domain.

Protein cellular localization

Nucleus. Note: May target the CHRAC complex to heterochromatin.

Note

AntibodyPlus can customize BAZ1A antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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