Rabbit polyclonal BCHE antibody (A1460)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal BCHE antibody (A1460)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal BCHE antibody.

Alternative names:

Check alternative names for the antibody

Expand

E1 antibody, CHE1 antibody, CHE2 antibody
Acylcholine acylhydrolase antibody|BCHE antibody|Butyrylcholine esterase antibody|CHE1 antibody|CHE2 antibody|CHLE_HUMAN antibody|Choline esterase II antibody|Cholinesterase (serum) 2 antibody|Cholinesterase 1 antibody|Cholinesterase antibody|E1 antibody|Pseudocholinesterase antibody|Pseudocholinesterase E1 antibody|Anti-Butyrylcholinesterase antibody (ab154763)

SCBT cat No: sc-46801|sc-377403|sc-46803|

Name

Rabbit polyclonal BCHE antibody

Catalogue No.

A1460

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human BCHE

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 68kDa/Observed: Refer to Figures

Formulation

BCHE antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

BCHE antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

E1 antibody, CHE1 antibody, CHE2 antibody

Database links

Human UniProt/Swiss-Prot:P06276

Protein names

E1, CHE1, CHE2

Protein function

Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.

Protein tissue specificity

Detected in blood plasma (at protein level). Present in most cells except erythrocytes.

Protein sequence and domain

Belongs to the type-B carboxylesterase/lipase family.

Protein post-translational modifications

N-glycosylated. No other PTM detected . The major N-glycan structures are of the complex diantennary type with 1 and 2 N-acetylneuraminic acid molecules (Neu5Ac) making up approximately 33% and 47% of the total N-glycans, respectively. Only low amounts of fucosylated diantennary N-glycans are detected (approximately 2%). Triantennary N-glycans with or without fucose amount to approximately 13%, whereas 5% of the total N-glycans are of the oligomannosidic or hybrid type.

Protein cellular localization

Secreted .

Background

Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.

Note

AntibodyPlus can customize BCHE antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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