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Rabbit polyclonal BEST1 antibody (A3022)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal BEST1 antibody.
Check alternative names for the antibodyExpand
ARB antibody|BEST 1 antibody|BEST antibody|Best disease antibody|Best macular dystrophy antibody|BEST1 antibody|BEST1_HUMAN antibody|Best1V1Delta2 antibody|Bestrophin 1 antibody|Bestrophin-1 antibody|Bestrophin1 antibody|BMD antibody|mBest1 antibody|RP50 antibody|TU15B antibody|Vitelliform macular dystrophy 2 antibody|Vitelliform macular dystrophy antibody|Vitelliform macular dystrophy protein 2 antibody|VMD 2 antibody|VMD2 antibody|Anti-Bestrophin antibody [E6-6] (ab2182)
SCBT cat No: sc-22027|sc-32792|sc-292163|
Rabbit polyclonal BEST1 antibody
|Catalogue No.|| |
Human, Mouse, Rat
A synthetic peptide of human BEST1
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 68kDa/Observed: Refer to figures
BEST1 antibody was tube-contained.
BEST1 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
Forms calcium-sensitive chloride channels. Highly permeable to bicarbonate.
|Protein tissue specificity|| |
Predominantly expressed in the basolateral membrane of the retinal pigment epithelium.
|Protein sequence and domain|| |
Belongs to the bestrophin family.
|Protein post-translational modifications|| |
Phosphorylated by PP2A.
|Protein cellular localization|| |
Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane .
This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]
AntibodyPlus can customize BEST1 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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