Rabbit polyclonal BMPR2 antibody (A5666)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal BMPR2 antibody (A5666)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:200 – 1:1000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal BMPR2 antibody.

Alternative names:

Check alternative names for the antibody

Expand

BMR2 antibody, PPH1 antibody, BMPR3 antibody, BRK-3 antibody, T-ALK antibody, BMPR-II antibody
BMP type II receptor antibody|BMP type-2 receptor antibody|BMPR 2 antibody|BMPR 3 antibody|BMPR II antibody|BMPR-2 antibody|BMPR-II antibody|Bmpr2 antibody|BMPR2_HUMAN antibody|BMPR3 antibody|BMPRII antibody|BMR 2 antibody|BMR2 antibody|Bone morphogenetic protein receptor type 2 antibody|Bone morphogenetic protein receptor type II antibody|Bone morphogenetic protein receptor type-2 antibody|Bone morphogenic protein receptor type II serine threonine kinase antibody|BRK 3 antibody|BRK3 antibody|PPH 1 antibody|PPH1 antibody|Serine threonine kinase type II activin receptor like kinase antibody|T ALK antibody|TALK antibody|Type II activin receptor like kinase antibody|Anti-BMPR2 antibody (ab96826)

SCBT cat No: sc-393304|sc-5682|sc-130704|sc-20737|sc-5683|sc-73752|

Name

Rabbit polyclonal BMPR2 antibody

Catalogue No.

A5666

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human BMPR2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:200 – 1:1000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 115kDa/Observed: Refer to Figures

Formulation

BMPR2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

BMPR2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

BMR2 antibody, PPH1 antibody, BMPR3 antibody, BRK-3 antibody, T-ALK antibody, BMPR-II antibody

Database links

Human UniProt/Swiss-Prot:Q13873

Protein names

BMR2, PPH1, BMPR3, BRK-3, T-ALK, BMPR-II

Protein function

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.

Protein tissue specificity

Highly expressed in heart and liver.

Protein sequence and domain

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.; Contains 1 protein kinase domain.

Protein cellular localization

Cell membrane ; Single-pass type I membrane protein.

Background

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.

Research area

All research areas>Membrane Receptors>BMP Receptor
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize BMPR2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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