Rabbit polyclonal BNIP1 antibody (A7263)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal BNIP1 antibody (A7263)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

NIP1 antibody, SEC20 antibody, TRG-8 antibody
BCL2 adenovirus E1B 19kD interacting protein 1 antibody|TRG-8 antibody|TRG8 antibody|Vesicle transport protein SEC20 antibody|Anti-BNIP1 antibody [2B3] (ab170160)

SCBT cat No: sc-135848|sc-1713|

Name

Rabbit polyclonal BNIP1 antibody

Catalogue No.

A7263

Reactivity

Human

Immunogen

Recombinant protein of human BNIP1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 26kDa/Observed: Refer to figures

Formulation

BNIP1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

BNIP1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

NIP1 antibody, SEC20 antibody, TRG-8 antibody

Database links

Human UniProt/Swiss-Prot:Q12981

Protein names

NIP1, SEC20, TRG-8

Protein function

SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy.

Protein tissue specificity

Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine.

Protein sequence and domain

Belongs to the SEC20 family.

Protein post-translational modifications

Lys-63′-linked polyubiquitination by RNF185 allows recruiting of autophagy receptor SQSTM1, which simultaneously binds both ubiquitin and LC3 to link ubiquitination and autophagy.

Protein cellular localization

Mitochondrion. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.

Background

This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. In addition, this protein is involved in vesicle transport into the endoplasmic reticulum. Alternative splicing of this gene results in four protein products with identical N- and C-termini.

Research area

All research areas>Tumor Suppressor/Apoptosis>BNIP
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize BNIP1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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