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Rabbit polyclonal BPGM antibody (A7880)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal BPGM antibody.
Check alternative names for the antibodyExpand
2 antibody|2,3-bisphosphoglycerate mutase antibody|2,3-bisphosphoglycerate mutase, erythrocyte antibody|2,3-bisphosphoglycerate synthase antibody|2,3-diphosphoglycerate mutase antibody|3-bisphosphoglycerate mutase antibody|3-bisphosphoglycerate synthase antibody|3-diphosphoglycerate mutase antibody|Ab2 098 antibody|AI323730 antibody|AL022789 antibody|Bisphosphoglycerate mutase antibody|BPG dependent PGAM antibody|BPG-dependent PGAM antibody|Bpgm antibody|C86192 antibody|DPGM antibody|Erythrocyte 2,3 bisphosphoglycerate mutase antibody|erythrocyte antibody|PMGE_HUMAN antibody|Anti-BPGM antibody (ab97497)
SCBT cat No: sc-393964|sc-373819|sc-376578|sc-82787|
Rabbit polyclonal BPGM antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human BPGM
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 30kDa/Observed: Refer to figures
BPGM antibody was tube-contained.
BPGM antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 126.96.36.199) and phosphatase (EC 188.8.131.52) activities.
|Protein tissue specificity|| |
Expressed in red blood cells. Expressed in non-erythroid cells of the placenta; present in the syncytiotrophoblast layer of the placental villi at the feto-maternal interface (at protein level).
|Protein sequence and domain|| |
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
|Protein post-translational modifications|| |
Glycation of Lys-159 in diabetic patients inactivates the enzyme.
2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.
AntibodyPlus can customize BPGM antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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