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Rabbit polyclonal BPI antibody (A5338)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal BPI antibody.
Check alternative names for the antibodyExpand
rBPI antibody, BPIFD1 antibody
Bactericidal permeability-increasing protein antibody|bactericidal/permeability-increasing protein antibody|BPI antibody|BPI fold containing family D, member 1 antibody|BPIFD1 antibody|CAP 57 antibody|rBPI antibody|recombinant BPI holoprotein, rBPI antibody|Anti-BPI antibody [EPR12350(B)] (ab175231)
SCBT cat No: sc-365309|sc-23292|sc-514434|sc-514212|
Rabbit polyclonal BPI antibody
|Catalogue No.|| |
Recombinant protein of human BPI
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 54kDa/Observed: Refer to Figures
BPI antibody was tube-contained.
BPI antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
rBPI antibody, BPIFD1 antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
|Protein tissue specificity|| |
Restricted to cells of the myeloid series.
|Protein sequence and domain|| |
The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.; The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
|Protein cellular localization|| |
Secreted . Cytoplasmic granule membrane . Note: Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms.
AntibodyPlus can customize BPI antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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