Rabbit polyclonal BPI antibody (A5338)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal BPI antibody (A5338)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal BPI antibody.

Alternative names:

Check alternative names for the antibody

Expand

rBPI antibody, BPIFD1 antibody
Bactericidal permeability-increasing protein antibody|bactericidal/permeability-increasing protein antibody|BPI antibody|BPI fold containing family D, member 1 antibody|BPIFD1 antibody|CAP 57 antibody|rBPI antibody|recombinant BPI holoprotein, rBPI antibody|Anti-BPI antibody [EPR12350(B)] (ab175231)

SCBT cat No: sc-365309|sc-23292|sc-514434|sc-514212|

Name

Rabbit polyclonal BPI antibody

Catalogue No.

A5338

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human BPI

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 54kDa/Observed: Refer to Figures

Formulation

BPI antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

BPI antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

rBPI antibody, BPIFD1 antibody

Database links

Human UniProt/Swiss-Prot:P17213

Protein names

rBPI, BPIFD1

Protein function

The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.

Protein tissue specificity

Restricted to cells of the myeloid series.

Protein sequence and domain

The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.; The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

Protein cellular localization

Secreted . Cytoplasmic granule membrane . Note: Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.

Background

This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms.

Note

AntibodyPlus can customize BPI antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!