Rabbit polyclonal BRIP1 antibody (A6804)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal BRIP1 antibody (A6804)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal BRIP1 antibody.

Alternative names:

Check alternative names for the antibody

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OF antibody, BACH1 antibody, FANCJ antibody
ATP dependent RNA helicase BRIP1 antibody|ATP-dependent RNA helicase BRIP1 antibody|BACH 1 antibody|BRAC 1 Associated C Terminal Helicase 1 antibody|BRCA 1 Interacting Protein 1 antibody|BRCA1 binding helicase like protein BACH1 antibody|BRCA1 interacting protein C terminal helicase 1 antibody|BRCA1-associated C-terminal helicase 1 antibody|BRCA1-interacting protein 1 antibody|BRCA1-interacting protein C-terminal helicase 1 antibody|BRCA1/BRCA2 associated helicase 1 antibody|BRIP 1 antibody|BRIP1 antibody|FANCJ antibody|FANCJ_HUMAN antibody|Fanconi anemia group J protein antibody|FLJ90232 antibody|MGC126521 antibody|MGC126523 antibody|OF antibody|Protein FACJ antibody|Anti-BACH1/BRIP1 antibody (ab49657)

SCBT cat No: sc-28079|

Name

Rabbit polyclonal BRIP1 antibody

Catalogue No.

A6804

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human BRIP1

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 141kDa/Observed: Refer to figures

Formulation

BRIP1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

BRIP1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

OF antibody, BACH1 antibody, FANCJ antibody

Database links

Human UniProt/Swiss-Prot:Q9BX63

Protein names

OF, BACH1, FANCJ

Protein function

DNA-dependent ATPase and 5′ to 3′ DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.

Protein tissue specificity

Ubiquitously expressed, with highest levels in testis.

Protein sequence and domain

4Fe-4S iron-sulfur-binding is required for helicase activity.Belongs to the DEAD box helicase family. DEAH subfamily.; Contains 1 helicase ATP-binding domain.

Protein post-translational modifications

Phosphorylated. Phosphorylation is necessary for interaction with BRCA1, and is cell-cycle regulated.; Acetylation at Lys-1249 facilitates DNA end processing required for repair and checkpoint signaling.

Protein cellular localization

Nucleus .

Background

The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations.

Note

AntibodyPlus can customize BRIP1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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