Rabbit Polyclonal C4a/b antibody (STJ97237)

$99.00$319.00

Reactivity: Human
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal C4a/b antibody (STJ97237)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC-P 1:100-1:300; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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C4A antibody, CO4 antibody, CPAMD2 antibody,|Acidic complement C4 antibody|C3 and PZP like alpha 2 macroglobulin domain containing protein 2 antibody|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 antibody|C4a anaphylatoxin antibody|C4A antibody|C4AD antibody|CO4A_HUMAN antibody|Complement C4 A antibody|Complement C4 gamma chain antibody|Complement component 4A antibody|Complement component 4A preproprotein antibody|CPAMD2 antibody|RG antibody|Rodgers form of C4 antibody|Anti-C4a antibody [EPR10143] (ab170942)
SCBT cat No: sc-80612|sc-80611|sc-58931|sc-58932|sc-101469|sc-271181|sc-23483|sc-25815|sc-74524|sc-25816|

 

Name

C4a/b Polyclonal Antibody

Catalogue No.

STJ97237

Reactivity

Human

Specificity

C4a/b Polyclonal Antibody detects endogenous levels of C4a/b protein.

Immunogen

Synthesized peptide derived from C4a/b at AA range 721-770

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC-P 1:100-1:300; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Formulation

C4a/b Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

C4a/b Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Complement C4-A antibody, Acidic complement C4 antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 antibody

Database links

Human UniProt/Swiss-Prot:P0C0L4 ;Human Entrez Gene: 720;

Protein names

Complement C4-A , Acidic complement C4 , C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2

Involvement in disease

Complement component 4A deficiency (C4AD) [MIM:614380]: A rare defect of the complement classical pathway associated with the development of autoimmune disorders, mainly systemic lupus with or without associated glomerulonephritis. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Systemic lupus erythematosus (SLE) [MIM:152700]: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. . Note: Disease susceptibility is associated with variations affecting the gene represented in this entry. Interindividual copy-number variation (CNV) of complement component C4 and associated polymorphisms result in different susceptibilities to SLE. The risk of SLE susceptibility has been shown to be significantly increased among subjects with only two copies of total C4. A high copy number is a protective factor against SLE.

Research area

All research areas>GDP/GTP Binding Proteins>C4G
(View all antibody categories related to GDP/GTP Binding Proteins)

Note

AntibodyPlus can customize C4a/b Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


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Antibody customer reviews & validation data - 158

Validation data ID: 158

Submission date: 2017-03-24

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Result figure:
  • Result figure
  • Result figure

Figure description:

staining of mouse brain section, and images show part of cortex as well as hippocampus area. Negative control was stained the same way except that no primary antibody was applied.

Product name

Anti-C4 a/b antibody

Product catalog No.

STJ97237

Product type

Primary antibody

Supplier

St John's Laboratory Ltd

Application type

Immunohistochemistry (IHC)

Antibody specificity rating

Fair

Antibody overall rating

Fair

Your comments

Great service. Tested the antibody on mouse brain sample, however, it dosen't give a very specific signal.

Detailed protocol

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