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Rabbit Polyclonal C4a/b antibody (STJ97237)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC-P 1:100-1:300; ELISA 1:10000;
Recommended protocols: check protocols
Click or hover above images to see image description for C4a/b Polyclonal Antibody.
Check alternative names for the antibodyExpand
C4A antibody, CO4 antibody, CPAMD2 antibody,|Acidic complement C4 antibody|C3 and PZP like alpha 2 macroglobulin domain containing protein 2 antibody|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 antibody|C4a anaphylatoxin antibody|C4A antibody|C4AD antibody|CO4A_HUMAN antibody|Complement C4 A antibody|Complement C4 gamma chain antibody|Complement component 4A antibody|Complement component 4A preproprotein antibody|CPAMD2 antibody|RG antibody|Rodgers form of C4 antibody|Anti-C4a antibody [EPR10143] (ab170942)
SCBT cat No: sc-80612|sc-80611|sc-58931|sc-58932|sc-101469|sc-271181|sc-23483|sc-25815|sc-74524|sc-25816|
C4a/b Polyclonal Antibody
|Catalogue No.|| |
C4a/b Polyclonal Antibody detects endogenous levels of C4a/b protein.
Synthesized peptide derived from C4a/b at AA range 721-770
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC-P 1:100-1:300; ELISA 1:10000;
C4a/b Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
C4a/b Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Complement C4-A antibody, Acidic complement C4 antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 antibody
|Database links|| |
Human UniProt/Swiss-Prot:<a href="http://www.uniprot.org/uniprot/P0C0L4">P0C0L4 </a>;Human Entrez Gene: <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=720/721">720</a>;
|Protein names|| |
Complement C4-A , Acidic complement C4 , C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2
|Involvement in disease|| |
Complement component 4A deficiency (C4AD) [MIM:614380]: A rare defect of the complement classical pathway associated with the development of autoimmune disorders, mainly systemic lupus with or without associated glomerulonephritis. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Systemic lupus erythematosus (SLE) [MIM:152700]: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. . Note: Disease susceptibility is associated with variations affecting the gene represented in this entry. Interindividual copy-number variation (CNV) of complement component C4 and associated polymorphisms result in different susceptibilities to SLE. The risk of SLE susceptibility has been shown to be significantly increased among subjects with only two copies of total C4. A high copy number is a protective factor against SLE.
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/GDPGTP-Binding-Proteins/">GDP/GTP Binding Proteins</a>><a href="http://antibodyplus.com/product-tag/C4G/">C4G</a><br><a href="http://antibodyplus.com/product-tag/GDPGTP-Binding-Proteins/"> (View all antibody categories related to GDP/GTP Binding Proteins)</a>
AntibodyPlus can customize C4a/b Antibody according to your requirement, including bulk product size,etc. Please contact <a href="mailto:firstname.lastname@example.org">email@example.com</a>. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
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Antibody customer reviews & validation data - 158
Validation data ID: 158
Submission date: 2017-03-24
staining of mouse brain section, and images show part of cortex as well as hippocampus area. Negative control was stained the same way except that no primary antibody was applied.
Anti-C4 a/b antibody
Product catalog No.
St John's Laboratory Ltd
Antibody specificity rating
Antibody overall rating
Great service. Tested the antibody on mouse brain sample, however, it dosen't give a very specific signal.
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