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Rabbit polyclonal C4BPB antibody (A6362)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:100 IF 1:50 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal C4BPB antibody.
Check alternative names for the antibodyExpand
C4b binding protein beta chain antibody|C4b-binding protein beta chain antibody|C4BP antibody|C4BPB antibody|C4BPB_HUMAN antibody|Complement component 4 binding protein beta antibody|Complement component 4 binding protein beta chain antibody|Complement component 4-binding protein beta antibody|OTTHUMP00000034288 antibody|OTTHUMP00000034289 antibody|OTTHUMP00000034375 antibody|OTTHUMP0000003474 antibody|Proline rich protein antibody|PRP antibody|Anti-C4 binding protein antibody [EPR17101] (ab199430)
SCBT cat No: sc-65970|sc-17214|sc-398720|sc-292601|
Rabbit polyclonal C4BPB antibody
|Catalogue No.|| |
Recombinant protein of human C4BPB
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 28kDa/Observed: Refer to Figures
C4BPB antibody was tube-contained.
C4BPB antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
|Protein sequence and domain|| |
Contains 3 Sushi (CCP/SCR) domains.
|Protein cellular localization|| |
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.
AntibodyPlus can customize C4BPB antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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