Rabbit polyclonal C8B antibody (A8324)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal C8B antibody (A8324)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal C8B antibody.

Alternative names:

Check alternative names for the antibody

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C82 antibody
C8A antibody|C8B antibody|C8G antibody|Complement component 8 subunit alpha antibody|Complement component 8 subunit beta antibody|complement component 8, alpha polypeptide antibody|complement component 8, beta polypeptide antibody|complement component 8, gamma polypeptide antibody|Complement component C8 alpha chain antibody|Complement component C8 beta chain antibody|Complement component C8 gamma chain antibody|MGC142186 antibody|MGC163447 antibody|Anti-C8 antibody [056B-373] (ab59140)

SCBT cat No: sc-107174|sc-515150|sc-107176|sc-107177|

Name

Rabbit polyclonal C8B antibody

Catalogue No.

A8324

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human C8B

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 67kDa/Observed: Refer to figures

Formulation

C8B antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

C8B antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

C82 antibody

Database links

Human UniProt/Swiss-Prot:P07358

Protein names

C82

Protein function

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.

Protein sequence and domain

Belongs to the complement C6/C7/C8/C9 family.; Contains 1 EGF-like domain.; Contains 1 LDL-receptor class A domain.; Contains 1 MACPF domain.; Contains 2 TSP type-1 domains.

Protein post-translational modifications

N-glycosylated; contains one or two bound glycans. Not O-glycosylated.

Protein cellular localization

Secreted.

Background

This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.

Research area

All research areas>Lymphocyte Signaling>Complement Pathway Protein
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize C8B antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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