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Rabbit polyclonal C8B antibody (A8324)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal C8B antibody.
Check alternative names for the antibodyExpand
C8A antibody|C8B antibody|C8G antibody|Complement component 8 subunit alpha antibody|Complement component 8 subunit beta antibody|complement component 8, alpha polypeptide antibody|complement component 8, beta polypeptide antibody|complement component 8, gamma polypeptide antibody|Complement component C8 alpha chain antibody|Complement component C8 beta chain antibody|Complement component C8 gamma chain antibody|MGC142186 antibody|MGC163447 antibody|Anti-C8 antibody [056B-373] (ab59140)
SCBT cat No: sc-107174|sc-515150|sc-107176|sc-107177|
Rabbit polyclonal C8B antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human C8B
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 67kDa/Observed: Refer to figures
C8B antibody was tube-contained.
C8B antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
|Protein sequence and domain|| |
Belongs to the complement C6/C7/C8/C9 family.; Contains 1 EGF-like domain.; Contains 1 LDL-receptor class A domain.; Contains 1 MACPF domain.; Contains 2 TSP type-1 domains.
|Protein post-translational modifications|| |
N-glycosylated; contains one or two bound glycans. Not O-glycosylated.
|Protein cellular localization|| |
This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.
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|Product type|| |
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