Rabbit polyclonal C9 antibody (A5622)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal C9 antibody (A5622)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

C9D antibody, ARMD15 antibody
C9 antibody|C9 deficiency antibody|C9 deficiency with dermatomyositis antibody|CO9_HUMAN antibody|Complement component 9 antibody|Complement component 9 deficiency antibody|Complement component C9 antibody|Complement component C9b antibody|Anti-C9 antibody [aE11] (ab90801)

SCBT cat No: sc-58935|sc-30352|sc-368573|sc-368572|sc-134288|

Name

Rabbit polyclonal C9 antibody

Catalogue No.

A5622

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human C9

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 63kDa/Observed: Refer to figures

Formulation

C9 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

C9 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

C9D antibody, ARMD15 antibody

Database links

Human UniProt/Swiss-Prot:P02748

Protein names

C9D, ARMD15

Protein function

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.

Protein tissue specificity

Plasma.

Protein sequence and domain

Belongs to the complement C6/C7/C8/C9 family.; Contains 1 EGF-like domain.; Contains 1 LDL-receptor class A domain.; Contains 1 MACPF domain.; Contains 1 TSP type-1 domain.

Protein post-translational modifications

Thrombin cleaves factor C9 to produce C9a and C9b.; Phosphorylation sites are present in the extracellular medium.

Protein cellular localization

Secreted. Cell membrane; Multi-pass membrane protein. Note: Secreted as soluble monomer. Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore.

Background

This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency.

Note

AntibodyPlus can customize C9 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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