Rabbit polyclonal CA9 antibody (A1658)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CA9 antibody (A1658)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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MN antibody, CAIX antibody
CA-IX antibody|CA9 antibody|CAH9_HUMAN antibody|CAIX antibody|Carbonate dehydratase IX antibody|Carbonic anhydrase 9 antibody|Carbonic anhydrase IX antibody|Carbonic dehydratase antibody|G250 antibody|Membrane antigen MN antibody|MN antibody|P54/58N antibody|pMW1 antibody|RCC associated protein G250 antibody|RCC-associated antigen G250 antibody|Renal cell carcinoma-associated antigen G250 antibody|Anti-Carbonic Anhydrase IX antibody (ab15086)

SCBT cat No: sc-365900|sc-25599|sc-25600|

Name

Rabbit polyclonal CA9 antibody

Catalogue No.

A1658

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CA9

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 50kDa/Observed: Refer to figures

Formulation

CA9 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CA9 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MN antibody, CAIX antibody

Database links

Human UniProt/Swiss-Prot:Q16790

Protein names

MN, CAIX

Protein function

Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.

Protein tissue specificity

Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.

Protein sequence and domain

Belongs to the alpha-carbonic anhydrase family.; Contains 1 alpha-carbonic anhydrase domain.

Protein post-translational modifications

Asn-346 bears high-mannose type glycan structures.

Protein cellular localization

Nucleus . Nucleus, nucleolus . Cell membrane ; Single-pass type I membrane protein . Cell projection, microvillus membrane ; Single-pass type I membrane protein . Note: Found on the surface microvilli and in the nucleus, particularly in nucleolus.

Background

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.

Research area

All research areas>Synthesis and Degradation>Carbonic Anhydrases
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize CA9 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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