Rabbit Polyclonal CACNA2D3 antibody (A10315)


Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal CACNA2D3 antibody (A10315)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:1000 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody


HSA272268 antibody;
CA2D3_HUMAN antibody|Cacna2d3 antibody|Calcium channel alpha2 delta3 subunit antibody|Calcium channel voltage dependent alpha 2/delta subunit 3 antibody|Calcium channel voltage-dependent alpha 2/delta 3 subunit antibody|HSA272268 antibody|Voltage dependent calcium channel subunit alpha 2/delta 3 antibody|Voltage-dependent calcium channel subunit delta-3 antibody|Voltage-gated calcium channel subunit alpha-2/delta-3 antibody|Anti-CACNA2D3 antibody (ab102939)

SCBT cat No: sc-99322|sc-99323|sc-99324|


Rabbit Polyclonal CACNA2D3 antibody

Catalogue No.



Human, Mouse, Rat


Recombinant protein of human CACNA2D3











Molecular weight



CACNA2D3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


Affinity purification


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HSA272268 antibody;

Protein names


Protein function

The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) but not T-type (CACNA1G) (By similarity).

Protein tissue specificity

Only detected in brain. Not present in lung, testis, aorta, spleen, jejunum, ventricular muscle and kidney (at protein level). According to PubMed:11687876, it is brain-specific, while according to PubMed:11245980, it is widely expressed.

Protein sequence and domain

Belongs to the calcium channel subunit alpha-2/delta family.; Contains 1 cache domain.; Contains 1 VWFA domain. The MIDAS-like motif in the VWFA domain binds divalent metal cations and is required to promote trafficking of the alpha-1 (CACNA1) subunit to the plasma membrane by an integrin-like switch.

Protein post-translational modifications

N-glycosylated.; May be proteolytically processed into subunits alpha-2-3 and delta-3 that are disulfide-linked. It is however unclear whether such cleavage really takes place in vivo and has a functional role (By similarity).

Protein cellular localization

Membrane ; Single-pass type I membrane protein .


This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.


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Product type

Primary antibody


ABclonal Inc.


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