Rabbit polyclonal CASK antibody (A2501)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CASK antibody (A2501)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CMG antibody, FGS4 antibody, LIN2 antibody, TNRC8 antibody, CAGH39 antibody, CAMGUK antibody, MICPCH antibody, MRXSNA antibody
CAGH39 antibody|Caki antibody|Calcium/calmodulin dependent serine protein kinase antibody|Calcium/calmodulin dependent serine protein kinase (MAGUK family) antibody|Calcium/calmodulin dependent serine protein kinase membrane associated guanylate kinase antibody|Calcium/calmodulin-dependent serine protein kinase antibody|CAMGUK antibody|CAMGUK protein antibody|CAMGUK, drosophila, homolog of antibody|casK antibody|CMG antibody|CSKP_HUMAN antibody|DXPri1 antibody|DXRib1 antibody|FGS4 antibody|FLJ22219 antibody|FLJ31914 antibody|hCASK antibody|LIN 2 antibody|Lin 2 homolog antibody|LIN2 antibody|Lin2 homolog antibody|MICPCH antibody|MRXSNA antibody|Pals3 antibody|Peripheral plasma membrane protein CASK antibody|Protein lin-2 homolog antibody|TNRC8 antibody|Trinucleotide repeat containing 8 antibody|Vertebtate LIN2 homolog antibody|Anti-CASK antibody [S56A-50] (ab99039)

SCBT cat No: sc-135857|sc-13158|sc-10777|

Name

Rabbit polyclonal CASK antibody

Catalogue No.

A2501

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CASK

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 105kDa/Observed: Refer to Figures

Formulation

CASK antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CASK antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CMG antibody, FGS4 antibody, LIN2 antibody, TNRC8 antibody, CAGH39 antibody, CAMGUK antibody, MICPCH antibody, MRXSNA antibody

Database links

Human UniProt/Swiss-Prot:O14936

Protein names

CMG, FGS4, LIN2, TNRC8, CAGH39, CAMGUK, MICPCH, MRXSNA

Protein function

Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.

Protein tissue specificity

Ubiquitous. Expression is significantly greater in brain relative to kidney, lung, and liver and in fetal brain and kidney relative to lung and liver.

Protein sequence and domain

The first L27 domain binds DLG1 and the second L27 domain probably binds LIN7.; The protein kinase domain mediates the interaction with FCHSD2.In the N-terminal section; belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.; Belongs to the MAGUK family.; Contains 1 guanylate kinase-like domain.; Contains 2 L27 domains.; Contains 1 PDZ (DHR) domain.; Contains 1 protein kinase domain.; Contains 1 SH3 domain.

Protein cellular localization

Nucleus . Cytoplasm . Cell membrane ; Peripheral membrane protein .

Background

This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, mental retardation and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize CASK antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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