Rabbit polyclonal CASP2 antibody (A5724)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CASP2 antibody (A5724)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CASP2 antibody.

Alternative names:

Check alternative names for the antibody

Expand

ICH1 antibody, NEDD2 antibody, CASP-2 antibody, NEDD-2 antibody, PPP1R57 antibody
CASP2 antibody|ICH-1L antibody|ICH1 antibody|NEDD-2 antibody|NEDD2 antibody|Protease ICH-1 antibody|Anti-Caspase-2L antibody (ab2251)

SCBT cat No: sc-53928|sc-514472|sc-15379|sc-623|sc-136218|sc-626|sc-625|sc-5292|sc-8985|sc-56053|

Name

Rabbit polyclonal CASP2 antibody

Catalogue No.

A5724

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CASP2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 50kDa/Observed: Refer to Figures

Formulation

CASP2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CASP2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ICH1 antibody, NEDD2 antibody, CASP-2 antibody, NEDD-2 antibody, PPP1R57 antibody

Database links

Human UniProt/Swiss-Prot:P42575

Protein names

ICH1, NEDD2, CASP-2, NEDD-2, PPP1R57

Protein function

Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.

Protein tissue specificity

Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.

Protein sequence and domain

Belongs to the peptidase C14A family.; Contains 1 CARD domain.

Protein post-translational modifications

The mature protease can process its own propeptide, but not that of other caspases.

Background

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer’s disease, Huntington’s disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research area

All research areas>Tumor Suppressor/Apoptosis>Caspase
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize CASP2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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