Rabbit polyclonal CAST antibody (A7634)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CAST antibody (A7634)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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BS-17 antibody, PLACK antibody
BS 17 antibody|Calpain inhibitor antibody|Calpastatin antibody|Cast antibody|Heart type calpastatin antibody|ICAL_HUMAN antibody|MGC9402 antibody|Sperm BS 17 component antibody|Sperm BS-17 component antibody|Anti-Calpastatin antibody (ab28252)

SCBT cat No: sc-7561|

Name

Rabbit polyclonal CAST antibody

Catalogue No.

A7634

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human CAST

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 77kDa/Observed: Refer to figures

Formulation

CAST antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CAST antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

BS-17 antibody, PLACK antibody

Database links

Human UniProt/Swiss-Prot:P20810

Protein names

BS-17, PLACK

Protein function

Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.

Protein sequence and domain

Each of the four flexible inhibitory domains can inhibit one calcium-bound calpain molecule by occupying both sides of the active site.Belongs to the protease inhibitor I27 (calpastatin) family.

Protein post-translational modifications

The N-terminus is blocked.

Background

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Research area

All research areas>Synthesis and Degradation>Calpastatin
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize CAST antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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