Rabbit polyclonal CBR1 antibody (A5446)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CBR1 antibody (A5446)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

CBR antibody, hCBR1 antibody, SDR21C1 antibody
15 hydroxyprostaglandin dehydrogenase [NADP+] antibody|15-hydroxyprostaglandin dehydrogenase [NADP+] antibody|Carbonyl reductase [NADPH] 1 antibody|Carbonyl Reductase 1 antibody|CBR 1 antibody|CBR1 antibody|CBR1_HUMAN antibody|CRN antibody|NADPH dependent carbonyl reductase 1 antibody|NADPH-dependent carbonyl reductase 1 antibody|Prostaglandin 9 ketoreductase antibody|Prostaglandin 9-ketoreductase antibody|Prostaglandin E(2) 9 reductase antibody|Prostaglandin-E(2) 9-reductase antibody|SDR21C1 antibody|Anti-CBR1 antibody (ab4148)

SCBT cat No: sc-390554|sc-70212|sc-292866|sc-100518|

Name

Rabbit polyclonal CBR1 antibody

Catalogue No.

A5446

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CBR1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 30kDa/Observed: Refer to Figures

Formulation

CBR1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CBR1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CBR antibody, hCBR1 antibody, SDR21C1 antibody

Database links

Human UniProt/Swiss-Prot:P16152

Protein names

CBR, hCBR1, SDR21C1

Protein function

NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.

Protein sequence and domain

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein cellular localization

Cytoplasm.

Background

The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene.

Research area

All research areas>Synthesis and Degradation>Carbonyl reductase
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize CBR1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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