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Rabbit polyclonal CBS antibody (A1427)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal CBS antibody.
Check alternative names for the antibodyExpand
HIP4 antibody,CBS antibody
AI047524 antibody|AI303044 antibody|Beta thionase antibody|Beta-thionase antibody|Cbs antibody|Cbs cystathionine beta-synthase antibody|CBS_HUMAN antibody|Cystathionine beta synthase antibody|Cystathionine beta-synthase antibody|EC 188.8.131.52 antibody|HIP 4 antibody|HIP4 antibody|Methylcysteine synthase antibody|MGC18856 antibody|MGC18895 antibody|MGC37300 antibody|OTTHUMP00000109416 antibody|OTTHUMP00000109418 antibody|Serine sulfhydrase antibody|Anti-CBS antibody (ab96252)
SCBT cat No: sc-133208|sc-515180|sc-133154|sc-271886|sc-67154|sc-46830|
Rabbit polyclonal CBS antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human CBS
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 61kDa/Observed: Refer to Figures
CBS antibody was tube-contained.
CBS antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
HIP4 antibody,CBS antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine . Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).
|Protein tissue specificity|| |
In the adult strongly expressed in liver and pancreas, some expression in heart and brain, weak expression in lung and kidney. In the fetus, expressed in brain, liver and kidney.
|Protein sequence and domain|| |
Belongs to the cysteine synthase/cystathionine beta-synthase family.; Contains 1 CBS domain.
|Protein cellular localization|| |
Cytoplasm . Nucleus .
The CBS gene encodes cystathionine beta-synthase, which catalyzes the first irreversible step of transsulfuration. The CBS enzyme is a homotetramer of 63-kD subunits and requires pyridoxal phosphate and heme for activity(PMID:11230183). CBS protein is localized in most areas of the brain, but predominantly in the cell bodies and neuronal processes of Purkinje cells and Ammon’s horn neurons(PMID:12588964). This antibody is specific to CBS.
AntibodyPlus can customize CBS antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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