No products in the cart.
Rabbit polyclonal CBX4 antibody (A6221)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:20 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal CBX4 antibody.
Check alternative names for the antibodyExpand
PC2 antibody, NBP16 antibody
CBX 4 antibody|CBX4 antibody|Cbx4 chromobox homolog 4 (Drosophila Pc class) antibody|CBX4_HUMAN antibody|Chromobox homolog 4 (Pc class homolog, Drosophila) antibody|Chromobox homolog 4 antibody|Chromobox protein homolog 4 antibody|E3 SUMO protein ligase CBX 4 antibody|E3 SUMO protein ligase CBX4 antibody|E3 SUMO-protein ligase CBX4 antibody|hPc 2 antibody|hPc2 antibody|NBP 16 antibody|NBP16 antibody|NS5ATP1 binding protein 16 antibody|Pc 2 antibody|Pc class 2 homolog antibody|Pc class homolog antibody|Pc class homolog Drosophila antibody|PC2 antibody|Polycomb 2 homolog antibody|Anti-CBX4 antibody (ab139815)
SCBT cat No: sc-517216|sc-19299|
Rabbit polyclonal CBX4 antibody
|Catalogue No.|| |
Recombinant protein of human CBX4
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 61kDa/Observed: Refer to Figures
CBX4 antibody was tube-contained.
CBX4 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
PC2 antibody, NBP16 antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131.; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ‘Lys-119’, rendering chromatin heritably changed in its expressibility.
|Protein tissue specificity|| |
|Protein sequence and domain|| |
The polyhistidine repeat may act as a targeting signal to nuclear speckles.Contains 1 chromo domain.
|Protein post-translational modifications|| |
Phosphorylated on Thr-497 by HIPK2 upon DNA damage. This phosphorylation stimulates E3 SUMO-protein ligase activity and promotes sumoylation on Lys-494, as well as sumoylation of other target proteins, such as HNRNPK.
|Protein cellular localization|| |
Nucleus . Nucleus speckle . Note: Localization to nuclear polycomb bodies is required for ZNF131 sumoylation .
AntibodyPlus can customize CBX4 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: