Rabbit polyclonal CCL2 antibody (A7277)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CCL2 antibody (A7277)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:100 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

HC11 antibody, MCAF antibody, MCP1 antibody, MCP-1 antibody, SCYA2 antibody, GDCF-2 antibody, SMC-CF antibody, HSMCR30 antibody
C-C motif chemokine 2 antibody|CCL2 antibody|CCL2_HUMAN antibody|Chemokine (C C motif) ligand 2 antibody|GDCF 2 antibody|GDCF-2 antibody|GDCF2 antibody|HC11 antibody|HSMCR30 antibody|JE antibody|MCAF antibody|MCP 1 antibody|MCP-1 antibody|MCP1 antibody|MGC9434 antibody|Monocyte chemoattractant protein 1 antibody|Monocyte chemotactic and activating factor antibody|Monocyte chemotactic protein 1 antibody|Monocyte secretory protein JE antibody|SCYA2 antibody|Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je) antibody|Small inducible cytokine A2 antibody|Small inducible cytokine subfamily A (Cys Cys), member 2 antibody|Small-inducible cytokine A2 antibody|SMC CF antibody|SMC-CF antibody|SMCCF antibody|Anti-MCP1 antibody (ab9669)

SCBT cat No: sc-32819|sc-130328|sc-32786|sc-32771|sc-1304|sc-32781|sc-52701|sc-28879|

Name

Rabbit polyclonal CCL2 antibody

Catalogue No.

A7277

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human CCL2

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:100 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 11kDa/Observed: Refer to figures

Formulation

CCL2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CCL2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HC11 antibody, MCAF antibody, MCP1 antibody, MCP-1 antibody, SCYA2 antibody, GDCF-2 antibody, SMC-CF antibody, HSMCR30 antibody

Database links

Human UniProt/Swiss-Prot:P13500

Protein names

HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HSMCR30

Protein function

Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

Protein tissue specificity

Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level).

Protein sequence and domain

Belongs to the intercrine beta (chemokine CC) family.

Protein post-translational modifications

Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant.

Protein cellular localization

Secreted.

Background

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

Research area

All research areas>Growth Factors and Hormones>MCP
(View all antibody categories related to Growth Factors and Hormones)

Note

AntibodyPlus can customize CCL2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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