Rabbit polyclonal CCNA2 antibody (A7632)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CCNA2 antibody (A7632)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CCNA2 antibody.

Alternative names:

Check alternative names for the antibody

Expand

CCN1 antibody, CCNA antibody
CCN1 antibody|CCNA antibody|Ccna2 antibody|CCNA2_HUMAN antibody|Cyclin A2 antibody|Cyclin-A antibody|Cyclin-A2 antibody|Anti-Cyclin A2 antibody [E23.1] (ab38)

SCBT cat No: sc-271682|

Name

Rabbit polyclonal CCNA2 antibody

Catalogue No.

A7632

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human CCNA2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 49kDa/Observed: Refer to figures

Formulation

CCNA2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CCNA2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CCN1 antibody, CCNA antibody

Database links

Human UniProt/Swiss-Prot:P20248

Protein names

CCN1, CCNA

Protein function

Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.

Protein sequence and domain

Belongs to the cyclin family. Cyclin AB subfamily.

Protein post-translational modifications

Polyubiquitinated via ‘Lys-11’-linked ubiquitin by the anaphase-promoting complex (APC/C), leading to its degradation by the proteasome. Deubiquitinated and stabilized by USP37 enables entry into S phase (By similarity).

Protein cellular localization

Nucleus . Cytoplasm . Note: Cytoplasmic when associated with SCAPER.

Background

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.

Research area

All research areas>Cell Cycle Proteins>Cyclin
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize CCNA2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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