Rabbit polyclonal CD160 antibody (A8189)

$69.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CD160 antibody (A8189)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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NK1 antibody, BY55 antibody, NK28 antibody
BY55 antibody|BY55_HUMAN antibody|CD160 antibody|CD160 antigen [Precursor] antibody|CD160 antigen antibody|CD160 delta Ig antibody|CD160 molecule antibody|CD160 transmembrane isoform antibody|FLJ46513 antibody|Natural killer cell receptor BY55 antibody|Natural killer cell receptor, immunoglobulin superfamily member antibody|NK1 antibody|NK28 antibody|Anti-CD160 antibody (ab202845)

SCBT cat No: sc-68910|

Name

Rabbit polyclonal CD160 antibody

Catalogue No.

A8189

Reactivity

Human

Immunogen

Recombinant protein of human CD160

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 20kDa/Observed: Refer to figures

Formulation

CD160 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CD160 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

NK1 antibody, BY55 antibody, NK28 antibody

Database links

Human UniProt/Swiss-Prot:O95971

Protein names

NK1, BY55, NK28

Protein function

Receptor showing broad specificity for both classical and non-classical MHC class I molecules.

Protein tissue specificity

Expressed in spleen, peripheral blood, and small intestine. Expression is restricted to functional NK and T cytotoxic lymphocytes.

Protein sequence and domain

Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Protein cellular localization

Cell membrane; Lipid-anchor, GPI-anchor.

Background

CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.

Note

AntibodyPlus can customize CD160 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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