Rabbit polyclonal CD177 antibody (A6550)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CD177 antibody (A6550)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

NB1 antibody, PRV1 antibody, HNA2A antibody, PRV-1 antibody, HNA-2a antibody, NB1 GP antibody
CD177 antibody|CD177 antigen antibody|CD177 molecule antibody|CD177_HUMAN antibody|HNA-2a antibody|HNA2A antibody|Human neutrophil alloantigen 2a antibody|NB1 antibody|NB1 glycoprotein antibody|NB1 GP antibody|Polycythemia rubra vera 1 antibody|Polycythemia rubra vera protein 1 antibody|PRV-1 antibody|PRV1 antibody|Anti-CD177 antibody [MEM-166] (ab8092)

SCBT cat No: sc-374291|sc-376329|sc-292261|

Name

Rabbit polyclonal CD177 antibody

Catalogue No.

A6550

Reactivity

Human

Immunogen

Recombinant protein of human CD177

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 46kDa/Observed: Refer to figures

Formulation

CD177 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CD177 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

NB1 antibody, PRV1 antibody, HNA2A antibody, PRV-1 antibody, HNA-2a antibody, NB1 GP antibody

Database links

Human UniProt/Swiss-Prot:Q8N6Q3

Protein names

NB1, PRV1, HNA2A, PRV-1, HNA-2a, NB1 GP

Protein tissue specificity

Highly expressed in normal bone marrow and weakly expressed in fetal liver. Expressed on neutrophils. Expressed in granulocytes of patients with polycythemia vera (PV) and with essential thrombocythemia (ET).

Protein sequence and domain

Contains 2 UPAR/Ly6 domains.

Protein post-translational modifications

N-glycosylated.; A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding).

Protein cellular localization

Cell membrane ; Lipid-anchor, GPI-anchor .

Background

This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener’s granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.

Research area

All research areas>Lymphocyte Signaling>CD177
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize CD177 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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