Rabbit polyclonal CD200R1 antibody (A8278)

$69.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CD200R1 antibody (A8278)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CD200R1 antibody.

Alternative names:

Check alternative names for the antibody

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OX2R antibody, MOX2R antibody, CD200R antibody, HCRTR2 antibody
CD 200R antibody|CD200 cell surface glycoprotein receptor antibody|CD200 receptor 1 antibody|Cd200r1 antibody|Cell surface glycoprotein CD200 receptor 1 antibody|Cell surface glycoprotein OX2 receptor 1 antibody|Cell surface glycoprotein OX2 receptor antibody|cell surface glycoprotein receptor CD200 antibody|CRTR 2 antibody|CRTR2 antibody|HCRTR2 antibody|MO2R1_HUMAN antibody|MOX2 receptor antibody|MOX2R antibody|OX2R antibody|Anti-CD200R antibody (ab92794)

SCBT cat No: sc-71765|sc-14394|sc-14390|sc-14392|

Name

Rabbit polyclonal CD200R1 antibody

Catalogue No.

A8278

Reactivity

Human

Immunogen

Recombinant protein of human CD200R1

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 37kDa/Observed: Refer to figures

Formulation

CD200R1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CD200R1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

OX2R antibody, MOX2R antibody, CD200R antibody, HCRTR2 antibody

Database links

Human UniProt/Swiss-Prot:Q8TD46

Protein names

OX2R, MOX2R, CD200R, HCRTR2

Protein function

Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.

Protein tissue specificity

Expressed in granulocytes, monocytes, most T-cells, neutrophils, basophils and a subset of NK, NKT and B-cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells.

Protein sequence and domain

Belongs to the CD200R family.; Contains 1 Ig-like C2-type (immunoglobulin-like) domain.; Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Protein post-translational modifications

The mature form of isoform 2 and/or isoform 4 starts at sequence position 27 of the corresponding isoform.

Protein cellular localization

Isoform 1: Cell membrane; Single-pass type I membrane protein.; Isoform 4: Cell membrane; Single-pass type I membrane protein.; Isoform 2: Secreted.; Isoform 3: Secreted.

Background

This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants.

Research area

All research areas>Lymphocyte Signaling>OX2
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize CD200R1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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