Rabbit polyclonal CD247 antibody (A2058)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CD247 antibody (A2058)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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T3Z antibody, CD3H antibody, CD3Q antibody, CD3Z antibody, TCRZ antibody, CD3-ZETA antibody
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SCBT cat No: sc-70617|sc-1239|sc-1124|sc-374281|sc-166435|sc-166275|sc-20919|sc-101411|sc-70628|sc-514271|sc-19658|

Name

Rabbit polyclonal CD247 antibody

Catalogue No.

A2058

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CD247

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 16kDa/Observed: Refer to Figures

Formulation

CD247 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CD247 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

T3Z antibody, CD3H antibody, CD3Q antibody, CD3Z antibody, TCRZ antibody, CD3-ZETA antibody

Database links

Human UniProt/Swiss-Prot:P20963

Protein names

T3Z, CD3H, CD3Q, CD3Z, TCRZ, CD3-ZETA

Protein function

Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.

Protein sequence and domain

The ITAM domains mediate interaction with SHB.Belongs to the CD3Z/FCER1G family.; Contains 3 ITAM domains.

Protein post-translational modifications

Phosphorylated on Tyr residues after T-cell receptor triggering.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Background

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Research area

All research areas>Lymphocyte Signaling>CD3
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize CD247 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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