Rabbit Polyclonal CD44 antibody (STJ92129)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, IF
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Antibody Validation Project, Antibody Trial Sample, Antibody Free Sample for your own antibody validation and submitting antibody reviews, AntibodyPlus

Rabbit Polyclonal CD44 antibody (STJ92129)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for CD44 Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

Expand

CD44 antibody, LHR antibody, MDU2 antibody, MDU3 antibody, MIC4 antibody,|LHR antibody|BA-1 antibody|CD 44 antibody|CD44 antibody|CD44 antigen antibody|CD44 molecule (Indian blood group) antibody|CD44 molecule antibody|CD44_HUMAN antibody|CDw44 antibody|Cell surface glycoprotein CD44 antibody|chondroitin sulfate proteoglycan 8 antibody|CSPG8 antibody|ECMR-III antibody|Epican antibody|Extracellular matrix receptor III antibody|GP90 lymphocyte homing/adhesion receptor antibody|HCELL antibody|hematopoietic cell E- and L-selectin ligand antibody|Heparan sulfate proteoglycan antibody|Hermes antigen antibody|homing function and Indian blood group system antibody|HSA antibody|HUTCH-I antibody|HUTCH1 antibody|Hyaluronate receptor antibody|IN antibody|MC56 antibody|MDU2 antibody|MDU3 antibody|MGC10468 antibody|MIC4 antibody|MUTCH1 antibody|PGP-1 antibody|PGP-I antibody|PGP1 antibody|Phagocytic glycoprotein 1 antibody|Phagocytic glycoprotein I antibody|Soluble CD44 antibody|Anti-CD44 antibody (ab157107)
SCBT cat No: sc-52536|

Name

CD44 Polyclonal Antibody

Catalogue No.

STJ92129

Reactivity

Human, Mouse, Rat

Specificity

CD44 Polyclonal Antibody detects endogenous levels of CD44 protein.

Immunogen

Synthesized peptide derived from CD44 at AA range 650-730

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

90 kDa

Formulation

CD44 Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

CD44 Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

CD44 antigen antibody, CDw44 antibody, Epican antibody, Extracellular matrix receptor III antibody, ECMR-III antibody, GP90 lymphocyte homing/adhesion receptor antibody, HUTCH-I antibody, Heparan sulfate proteoglycan antibody, Hermes antigen antibody, Hyaluronate receptor antibody, Phagocytic glycoprotein 1 antibody, PGP-1 antibody, Phagocytic glycoprotein I antibody, PGP-I antibody, CD antigen CD44 antibody

Database links

Human UniProt/Swiss-Prot:P16070;Mouse UniPort/Swiss-Prot: P15379;Rat UniProt/Swiss-Port: O08779;Human Entrez Gene: 960;Mouse Entrez Gene: 12505;Rat Entrez Gene: Rn.1120

Protein names

CD44 antigen , CDw44 , Epican , Extracellular matrix receptor III , ECMR-III , GP90 lymphocyte homing/adhesion receptor , HUTCH-I , Heparan sulfate proteoglycan , Hermes antigen , Hyaluronate receptor , Phagocytic glycoprotein 1 , PGP-1 , Phagocytic glycoprotein I , PGP-I , CD antigen CD44

Protein function

Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity).

Protein tissue specificity

Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.

Protein sequence and domain

The lectin-like LINK domain is responsible for hyaluronan binding. / Contains 1 Link domain.

Protein post-translational modifications

Proteolytically cleaved in the extracellular matrix by specific proteinases (possibly MMPs) in several cell lines and tumors. / N- and O-glycosylated. O-glycosylation contains more-or-less-sulfated chondroitin sulfate glycans, whose number may affect the accessibility of specific proteinases to their cleavage site(s). It is uncertain if O-glycosylation occurs on Thr-637 or Thr-638. / Phosphorylated; activation of PKC results in the dephosphorylation of Ser-706 (constitutive phosphorylation site), and the phosphorylation of Ser-672.

Protein cellular localization

Cell membrane / Single-pass type I membrane protein

Research area

All research areas>Membrane Receptors>HARE
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize CD44 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews
 

Immunofluorescence analysis of Rat lung tissue

1: CD44 Polyclonal Antibody(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Rat lung tissue

1: CD44 Polyclonal Antibody(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Rat kidney tissue

1: CD44 Polyclonal Antibody(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Rat kidney tissue

1: CD44 Polyclonal Antibody(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Mouse liver tissue

1: CD44 Polyclonal Antibody(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Mouse liver tissue

1: CD44 Polyclonal Antibody(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunohistochemical analysis of paraffin embedded Mouse testis tissue

1: CD44 Polyclonal Antibody was diluted at 1:200 (4 degree Celsius,overnight).
2: Sodium citrate pH 6.0 was used for antibody retrieval (>98 degree Celsius,20min).
3: Secondary antibody was diluted at 1:200 (room temperature, 30min). Negative control was used by secondary antibody only.


Welcome to AntibodyPlus!