Rabbit polyclonal CD55 antibody (A1228)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal CD55 antibody (A1228)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CD55 antibody.

Alternative names:

Check alternative names for the antibody

Expand

CR antibody, TC antibody, DAF antibody, CROM antibody,CD55 antibody
CD 55 antibody|CD55 antibody|CD55 antigen antibody|CD55 Cromer blood group system antibody|CD55 molecule antibody|CD55 molecule, decay accelerating factor for complement (Cromer blood group) antibody|Cd55a antibody|Complement decay accelerating factor antibody|Complement decay-accelerating factor antibody|Complement decay-accelerating factor, GPI-anchored antibody|CR antibody|CROM antibody|Cromer Blood Group antigen antibody|Cromer blood group system antibody|DAF antibody|Daf-GPI antibody|DAF_HUMAN antibody|Daf1 antibody|Dcay accelerating factor for complement (CD55, Cromer blood group system) antibody|Decay accelarating factor 1, isoform CRA_a antibody|Decay accelerating factor (GPI-form) antibody|Decay Accelerating Factor for Complement antibody|Decay accelerating factor GPI-form antibody|Decay accelerating factor soluble-form antibody|GPI-DAF antibody|TC antibody|Anti-CD55 antibody [MEM-118] (ab1422)

SCBT cat No: sc-21769|sc-53207|sc-59092|sc-9156|sc-133220|sc-7067|

Name

Rabbit polyclonal CD55 antibody

Catalogue No.

A1228

Reactivity

Human

Immunogen

Recombinant protein of human CD55

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 41kDa/Observed: Refer to Figures

Formulation

CD55 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CD55 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CR antibody, TC antibody, DAF antibody, CROM antibody,CD55 antibody

Database links

Human UniProt/Swiss-Prot:P08174

Protein names

CR, TC, DAF, CROM,CD55

Protein function

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.; (Microbial infection) Acts as a receptor for coxsackievirus A21, coxsackieviruses B1, B3 and B5 . Acts as a receptor for human enterovirus 70 and D68 (Probable) . Acts as a receptor for human echoviruses 6, 7, 11, 12, 20 and 21 .

Protein tissue specificity

Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.

Protein sequence and domain

The first Sushi domain (SCR1) is not necessary for function. SCR2 and SCR4 provide the proper conformation for the active site on SCR3 (By similarity).Belongs to the receptors of complement activation (RCA) family.; Contains 4 Sushi (CCP/SCR) domains.

Protein post-translational modifications

The Ser/Thr-rich domain is heavily O-glycosylated.

Protein cellular localization

Isoform 1: Cell membrane; Single-pass type I membrane protein.; Isoform 2: Cell membrane; Lipid-anchor, GPI-anchor.; Isoform 3: Secreted .; Isoform 4: Secreted .; Isoform 5: Secreted .; Isoform 6: Cell membrane ; Lipid-anchor, GPI-anchor .; Isoform 7: Cell membrane ; Lipid-anchor, GPI-anchor .

Background

This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Research area

All research areas>Lymphocyte Signaling>CD55
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize CD55 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!