Rabbit polyclonal CDC5L antibody (A5560)


Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CDC5L antibody (A5560)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CDC5L antibody.

Alternative names:

Check alternative names for the antibody


CDC5 antibody, CEF1 antibody, PCDC5RP antibody, CDC5-LIKE antibody, dJ319D22.1 antibody
CDC5 antibody||Anti-CDC5L antibody [2136C1a] (ab51320)

SCBT cat No: sc-135863|sc-81220|sc-398280|


Rabbit polyclonal CDC5L antibody

Catalogue No.



Human, Mouse, Rat


Recombinant protein of human CDC5L





Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100







Molecular weight

Predicted: 92kDa/Observed: Refer to Figures


CDC5L antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


CDC5L antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CDC5 antibody, CEF1 antibody, PCDC5RP antibody, CDC5-LIKE antibody, dJ319D22.1 antibody

Database links

Human UniProt/Swiss-Prot:Q99459

Protein names

CDC5, CEF1, PCDC5RP, CDC5-LIKE, dJ319D22.1

Protein function

DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).

Protein tissue specificity

Ubiquitously expressed in both fetal and adult tissues.

Protein sequence and domain

Belongs to the CEF1 family.; Contains 2 HTH myb-type DNA-binding domains.

Protein post-translational modifications

Phosphorylated on serine and threonine residues. Phosphorylation on Thr-411 and Thr-438 is required for CDC5L-mediated mRNA splicing. Has no effect on subcellular location nor on homodimerization. Phosphorylated in vitro by CDK2. Phosphorylation enhances interaction with PPP1R8.

Protein cellular localization

Nucleus . Nucleus speckle . Cytoplasm . Note: May shuttle between cytoplasm and nucleus.


The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.

Research area

All research areas>Cell Cycle Proteins>Cdc
(View all antibody categories related to Cell Cycle Proteins)


AntibodyPlus can customize CDC5L antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


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