Rabbit polyclonal CDC5L antibody (A5560)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal CDC5L antibody (A5560)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CDC5L antibody.

Alternative names:

Check alternative names for the antibody

Expand

CDC5 antibody, CEF1 antibody, PCDC5RP antibody, CDC5-LIKE antibody, dJ319D22.1 antibody
CDC5 antibody||Anti-CDC5L antibody [2136C1a] (ab51320)

SCBT cat No: sc-135863|sc-81220|sc-398280|

Name

Rabbit polyclonal CDC5L antibody

Catalogue No.

A5560

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CDC5L

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 92kDa/Observed: Refer to Figures

Formulation

CDC5L antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CDC5L antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CDC5 antibody, CEF1 antibody, PCDC5RP antibody, CDC5-LIKE antibody, dJ319D22.1 antibody

Database links

Human UniProt/Swiss-Prot:Q99459

Protein names

CDC5, CEF1, PCDC5RP, CDC5-LIKE, dJ319D22.1

Protein function

DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).

Protein tissue specificity

Ubiquitously expressed in both fetal and adult tissues.

Protein sequence and domain

Belongs to the CEF1 family.; Contains 2 HTH myb-type DNA-binding domains.

Protein post-translational modifications

Phosphorylated on serine and threonine residues. Phosphorylation on Thr-411 and Thr-438 is required for CDC5L-mediated mRNA splicing. Has no effect on subcellular location nor on homodimerization. Phosphorylated in vitro by CDK2. Phosphorylation enhances interaction with PPP1R8.

Protein cellular localization

Nucleus . Nucleus speckle . Cytoplasm . Note: May shuttle between cytoplasm and nucleus.

Background

The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.

Research area

All research areas>Cell Cycle Proteins>Cdc
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize CDC5L antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!