Rabbit polyclonal CDKN2B antibody (A5685)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CDKN2B antibody (A5685)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CDKN2B antibody.

Alternative names:

Check alternative names for the antibody

Expand

P15 antibody, MTS2 antibody, TP15 antibody, CDK4I antibody, INK4B antibody, p15INK4b antibody
CDK inhibitory protein antibody|CDK4B Inhibitor antibody|Cdkn2b antibody|CDN2B_HUMAN antibody|Cyclin dependent kinase 4 inhibitor B antibody|Cyclin Dependent Kinase Inhibitor 2B antibody|Cyclin dependent kinase inhibitor 2B p15 inhibits CDK4 antibody|Cyclin dependent kinases 4 and 6 binding protein antibody|Cyclin-dependent kinase 4 inhibitor B antibody|INK4B antibody|MTS 2 antibody|MTS-2 antibody|MTS2 antibody|Multiple tumor suppressor 2 antibody|Multiple Tumor Supressor 2 antibody|OTTHUMP00000021154 antibody|OTTHUMP00000021155 antibody|p14 CDK inhibitor antibody|p14 INK4b antibody|p14-INK4b antibody|P15 antibody|p15 CDK inhibitor antibody|p15 inhibits CDK4 antibody|p15 INK4b antibody|p15-INK4b antibody|p15INK4B antibody|TP 15 antibody|TP15 antibody|Anti-p15 INK4b antibody (ab53034)

SCBT cat No: sc-1429|

Name

Rabbit polyclonal CDKN2B antibody

Catalogue No.

A5685

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CDKN2B

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 15kDa/Observed: Refer to figures

Formulation

CDKN2B antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CDKN2B antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

P15 antibody, MTS2 antibody, TP15 antibody, CDK4I antibody, INK4B antibody, p15INK4b antibody

Database links

Human UniProt/Swiss-Prot:P42772

Protein names

P15, MTS2, TP15, CDK4I, INK4B, p15INK4b

Protein function

Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.

Protein tissue specificity

Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines.

Protein sequence and domain

Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.; Contains 4 ANK repeats.

Protein cellular localization

Cytoplasm . Note: Also found in the nucleus.

Background

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Research area

All research areas>Cell Cycle Proteins>p15
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize CDKN2B antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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