Rabbit polyclonal CENPC antibody (A6557)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CENPC antibody (A6557)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CENPC antibody.

Alternative names:

Check alternative names for the antibody

Expand

MIF2 antibody, hcp-4 antibody, CENP-C antibody, CENPC1 antibody
CENP-C 1 antibody|CENP-C antibody|CENPC_HUMAN antibody|CENPC1 antibody|Centromere autoantigen C antibody|Centromere autoantigen C1 antibody|Centromere protein C 1 antibody|Centromere protein C antibody|hcp-4 antibody|ICEN7 antibody|Interphase centromere complex protein 7 antibody|MIF2 antibody|Anti-CENPC antibody [EPR15939] (ab193666)

SCBT cat No: sc-166099|sc-22789|sc-11285|

Name

Rabbit polyclonal CENPC antibody

Catalogue No.

A6557

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human CENPC

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 106kDa/Observed: Refer to figures

Formulation

CENPC antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CENPC antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MIF2 antibody, hcp-4 antibody, CENP-C antibody, CENPC1 antibody

Database links

Human UniProt/Swiss-Prot:Q03188

Protein names

MIF2, hcp-4, CENP-C, CENPC1

Protein function

Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.

Protein sequence and domain

The MIF2 homology domain II targets centromeres and binds the alpha satellite DNA in vivo. The MIF2 homology domain III can induce CENPC dimerization/oligomerization.Belongs to the CENPC family.

Protein cellular localization

Nucleus . Chromosome, centromere, kinetochore . Note: Localizes exclusively in the kinetochore domain of centromeres.

Background

Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12.

Research area

All research areas>Cell Cycle Proteins>CENP
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize CENPC antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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