Rabbit polyclonal CES1 antibody (A1853)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CES1 antibody (A1853)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CEH antibody, REH antibody, TGH antibody, ACAT antibody, CE-1 antibody, CES2 antibody, HMSE antibody, SES1 antibody, HMSE1 antibody, PCE-1 antibody, hCE-1 antibody
ACAT antibody|Acyl coenzyme A cholesterol acyltransferase antibody|Acyl-coenzyme A:cholesterol acyltransferase antibody|Brain carboxylesterase hBr1 antibody|Carboxyesterase ES-3 antibody|Carboxylesterase antibody|Carboxylesterase 1 (monocyte/macrophage serine esterase 1) antibody|Carboxylesterase 1 antibody|Carboxylesterase 1 deficiency, included antibody|Carboxylesterase 2, formerly antibody|CE 1 antibody|CEH antibody|Ces-1 antibody|CES1 antibody|CES2 antibody|CESDD1 antibody|Cholesterol ester hydrolase, neutral, macrophage-derived antibody|Cholesteryl ester hydrolase antibody|Cocaine carboxylesterase antibody|EC 3.1.1.1 antibody|Egasyn antibody|ES-HTEL antibody|ES-x antibody|Es22 antibody|EST1_HUMAN antibody|Esterase 22 antibody|Esterase antibody|hCE 1 antibody|HMSE antibody|HMSE1 antibody|Liver carboxylesterase 1 antibody|Liver carboxylesterase 3 antibody|Methylumbelliferyl acetate deacetylase 1 antibody|MGC117365 antibody|MGC156521 antibody|Monocyte carboxylesterase deficiency, included antibody|Monocyte esterase deficiency, included antibody|Monocyte/macrophage serine esterase antibody|PCE-1 antibody|pI 5.5 esterase antibody|Proline-beta-naphthylamidase antibody|REH antibody|Retinyl ester hydrolase antibody|Serine esterase 1 antibody|Ses-1 antibody|SES1 antibody|TGH antibody|Triacylglycerol hydrolase antibody|Anti-Liver Carboxylesterase 1 antibody (ab45957)

SCBT cat No: sc-365249|sc-398236|sc-365248|sc-135021|

Name

Rabbit polyclonal CES1 antibody

Catalogue No.

A1853

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CES1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 63kDa/Observed: Refer to Figures

Formulation

CES1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CES1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CEH antibody, REH antibody, TGH antibody, ACAT antibody, CE-1 antibody, CES2 antibody, HMSE antibody, SES1 antibody, HMSE1 antibody, PCE-1 antibody, hCE-1 antibody

Database links

Human UniProt/Swiss-Prot:P23141

Protein names

CEH, REH, TGH, ACAT, CE-1, CES2, HMSE, SES1, HMSE1, PCE-1, hCE-1

Protein function

Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate.

Protein tissue specificity

Expressed predominantly in liver with lower levels in heart and lung.

Protein sequence and domain

Belongs to the type-B carboxylesterase/lipase family.

Protein post-translational modifications

Contains sialic acid.; Cleavage of the signal sequence can occur at 2 positions, either between Trp-17 and Gly-18 or between Gly-18 and His-19.

Protein cellular localization

Endoplasmic reticulum lumen .

Background

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

Note

AntibodyPlus can customize CES1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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